Primary Immunodeficiency Sorting Bay

Primary Immunodeficiency Sorting Bay

Eight traps, one move: identify the immune arm first, then use the lab clue that separates the look-alikes.

Commit first

A 10-month-old boy has recurrent otitis media, eczema, and petechiae. Labs show platelets 40,000 with low MPV, low IgM, and elevated IgA/IgE.

What's the diagnosis?

First move

Do not memorize the table. Diagnose the broken arm.

Read the infection pattern, pick the immune arm that failed, then use the feedback to lock the mechanism. This is the step that separates every disease on the page.

Pattern 1 / 5

2
The Eight + Near Misses: One Profile at a Time
Profile 1 / 12

3
Sort It: Pick the Immune Branch

Each finding belongs to one broken immune branch. Make the branch call before the disease name.

Finding 1 / 19

B Cell (Humoral)

T Cell (Cellular)

Combined

Phagocyte

Complement

4
Decision Tree: "This Kid Has Recurrent Infections"

Board stems give you a kid with infections. You need to work through the labs to find the deficiency. This is the algorithm.

Step 1: What TYPE of infections?
5
Elimination Game: 6 Clinical Scenarios

clinical vignettes. Four options, one correct. The explanation matters more than the answer.

6
Quiz: 12 Clinical Questions (randomized)

Every reload picks 6 from a pool of 14 and shuffles the answer order. No memorizing the pattern.

7
The Lineup: Pattern Profiles
Comparison 1 / 5

8
Clinical Photos: What These Patients Look Like

Tap any image to enlarge. These are the findings you need to recognize in clinical practice.

Sinusitis X-ray
Recurrent Sinusitis
Oral Candidiasis
Oral Candidiasis
Oral thrush on tongue
Thrush: Tongue
Frontal sinus inflammation
Frontal Sinusitis
Aspergillosis gross lung specimen
Aspergillosis (CGD)
Medically reviewed by Kaitlyn Cocuzzo, MD and Fatima Ali, DO · Last updated July 1, 2026 at 10:03 PM ET
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