Crossed pain-temperature loss plus dysphagia, hoarseness, Horner, vertigo, ataxia, and no limb weakness is lateral medulla. That is PICA.
Medically reviewed by Kaitlyn Cocuzzo, MD and Fatima Ali, DO Last updated 2026-07-13T16:16:47-04:00 (ET)
Before you scroll: A 67-year-old man develops vertigo, nausea, hoarseness, dysphagia, decreased gag reflex, ipsilateral facial pain and temperature loss, and contralateral body pain and temperature loss. Motor strength is preserved. Which artery is most likely occluded?
The crossed sensory pattern places the lesion in the brainstem, and the nucleus ambiguus signs localize it to lateral medulla. PICA hits lateral medulla and spares the corticospinal tract, so strength is preserved. AICA is one floor up in the pons and adds facial paralysis or hearing loss. Crossed pain-temperature + dysphagia/hoarseness + no weakness = PICA Wallenberg.
Brainstem floor check
PICA vs Its Look-Alikes
The artery answer follows the level: medulla, pons, medial medulla, or cortex.
PICA
Lateral medulla
SignatureIpsilateral face pain/temp loss plus contralateral body pain/temp loss