Adrenergic Receptors: Alpha vs Beta Effects
Alpha 1, alpha 2, beta 1, beta 2, beta 3. Where they live and what they do.
Beta blockers: predict the tissue response
Connect beta-receptor signaling to drug selection, heart-failure timing, airway and glucose risks, and poisoning care through visual models and clinical cases.
Gabapentinoids: Target, Exposure and Clinical Decisions
Vincristine neuropathy and vinca toxicities
Digoxin: stronger contraction, slower conduction, narrow margin
Build digoxin's pump mechanism, apply it to diagnosis and management, then extend the same logic to dosing, monitoring, interactions and counseling.
Antidiabetic drugs. Match the mechanism to the person
Choose glucose-lowering treatment by insulin physiology, cardiovascular and kidney disease, weight goals, hypoglycemia risk, and acute illness precautions.
Glucocorticoids and fragile bone
Explore how glucocorticoids disrupt bone remodeling, calcium balance, and strength, then apply risk-based fracture prevention through original cases.
Anabolic Steroids
Anabolic-androgenic steroids: nuclear receptor mechanism, HPG axis suppression, doping lab fingerprints, and board-style vignettes with interactive matching game.
Drug-Induced Mental Status Change and Tremor: Board Review
Stop blaming hypoxia or stroke when the medications did it. Trace why corticosteroids scramble cognition, why a beta-2 agonist shakes the hands, how theophylline seizes, and why a normal EEG and MRI point to a toxic or medication cause, not a structural one.
Antibiotics: connect the target to the infection
Choose antibiotics by bacterial target, infection site, resistance and patient risk, then apply those distinctions to treatment and adverse effects.
Antiviral Drugs: Mechanisms and Interactions
Ritonavir, the CYP3A4 grenade, and the drug-drug interactions that hospitalize.
Foscarnet | Activation, resistance and electrolyte safety
Test how foscarnet bypasses viral activation, then connect polymerase resistance, free calcium and renal clearance through diagrams and original cases.
General Anesthetics: MAC, Gases, and IV Agents
Interactive board review of general anesthetics: blood:gas onset, oil:gas potency, MAC, volatile anesthetic toxicity, malignant hyperthermia, nitrous oxide air-space expansion, and IV induction agents.
Antimetabolites & Drug Interactions
Antimetabolite chemotherapy for clinical practice: methotrexate, 5-FU, 6-MP, and cytarabine, their targets in nucleotide synthesis, rescue agents, and toxicities, fully interactive.
Cholinergic Pharmacology: Wet vs Dry Toxidromes
Cholinergic and anticholinergic pharmacology: muscarinic agonists and antimuscarinics, the wet SLUDGE toxidrome treated with atropine and pralidoxime versus the dry anticholinergic toxidrome treated with physostigmine, plus board-style walkthroughs.
Cisplatin: Mechanism & Toxicity
Interactive board review for cisplatin: DNA cross-linking mechanism, the bleomycin mix-up, nephrotoxicity, ototoxicity, neuropathy, prevention, and physician-reviewed board walkthroughs.
Toxidromes and antidotes: recognize the failing physiology
Read pupils, secretions, ventilation, ECG and acid-base findings together to recognize poisoning, select antidotes and identify urgent escalation.
Tyramine Crisis: MAOI Hypertensive Reaction
The tyramine reaction for clinical practice: why MAOIs plus aged cheese trigger a hypertensive crisis, the mechanism, and the foods to avoid, with interactive pharmacology.
Anesthesia Pharmacology: Local Anesthetics & Paralytics
Interactive anesthesia pharmacology review: local anesthetic sodium-channel blockade, amides and esters, epinephrine, acidic tissue, methemoglobinemia, bupivacaine cardiotoxicity, succinylcholine, nondepolarizing blockers, and malignant hyperthermia.
Opioid Intoxication and Naloxone
Alpha blockers: receptor to bedside
Build the receptor map, then use it for standing, urinary symptoms, drug families, and catecholamine responses.
Autonomic Nervous System: Wires, Receptors, Organs
Autonomic nervous system pharmacology for medical students: somatic versus autonomic wires, sympathetic and parasympathetic receptor maps, adrenal medulla and sweat gland exceptions, organ effects, and clinical walkthroughs.
Bleomycin: Pulmonary Fibrosis & the Free-Radical Killer
Why bleomycin scars the lungs while sparing the marrow: free-radical DNA breaks, low bleomycin hydrolase, oxygen and radiation potentiation, and how to tell it apart from cisplatin. Fully interactive.
Prostate Cancer Drugs
Prostate cancer drugs for clinical practice: GnRH agonists vs antagonists, anti-androgens, and the flare phenomenon, mapped onto the androgen axis, fully interactive.
Hypothalamic and Pituitary Drugs: Timing, Targets and Water
Statins and Bile Acid Sequestrants 🔒
Lipid-lowering drugs for clinical practice: statins inhibiting HMG-CoA reductase vs bile acid sequestrants, their LDL effects, and key toxicities like myopathy, fully interactive.