Anemias: explain cell size and marrow response
Interpret anemia through marrow response, iron availability, globin production and cell maturation, then distinguish hemolysis from failed production.
Hemolytic anemias: locate the destruction
Locate red-cell destruction, interpret immune testing, and distinguish inherited defects, complement injury and urgent fragmentation syndromes.
Iron Deficiency Anemia Workup
Ferritin, TIBC, transferrin saturation. The iron studies that nail IDA.
Macrocytic, Normocytic Anemias & PNH
B12 vs folate, hypersegmented neutrophils, and the PNH that hides as both.
Microcytic Anemias
Iron deficiency, thalassemia, anemia of chronic disease, sideroblastic, lead.
Lead Poisoning
Lead poisoning for clinical practice: ALA dehydratase and ferrochelatase inhibition, basophilic stippling, microcytic anemia, the neuro and GI signs, and chelation, interactive.
Benzene marrow toxicity and CBC monitoring
Clotting cascade: localize the defect, then explain the phenotype
Use thrombin-centered physiology, PT/aPTT patterns, mixing studies, bleeding phenotypes, anticoagulant targets, and DIC trends to localize hemostatic disorders.
Coagulation: connect assays to bleeding and thrombosis
Connect coagulation complexes, PT and aPTT, mixing studies and bleeding patterns to factor disorders, inhibitors, consumption and drug reversal.
Drugs of the Clotting Cascade
Heparin, warfarin, DOACs, tPA. Anticoagulants and thrombolytics by mechanism.
Hemophilia & the Coag Cascade
Factor VIII vs IX, X-linked recessive, and the joint bleeds that define hemophilia.
Platelets & Hemostasis
Quantitative vs qualitative defects. ITP, TTP, HUS, and the bleeding-time / PT / PTT panel that sorts them out.
Bleeding and Coagulation Disorder Decoder
Interactive medical board review for Bleeding and Coagulation Disorder Decoder: high-yield clues, traps, and physician-reviewed board walkthroughs.
Hemophilic arthropathy: from joint bleed to target joint
Trace joint bleeding into synovitis and cartilage damage, distinguish factor defects from mucosal bleeding, and act on infection or threatened-limb signs.
Platelet disorders: number, function and clinical pattern
Distinguish platelet counting errors, immune and consumptive disorders, marrow causes and receptor defects using clinical context and visible comparisons.
Disseminated Intravascular Coagulation
Factor VII Deficiency and Isolated Prolonged PT
Multiple Myeloma & MGUS
CRAB criteria, M-spike on SPEP, and lytic bone lesions. MGUS vs smoldering vs symptomatic myeloma.
Leukemias: ALL vs AML vs CLL vs CML
The four leukemias for boards: ALL, AML, CLL, and CML by age, blast type, and the defining clue (Auer rods, smudge cells, Philadelphia), in an interactive comparison.
Cancer Translocations: t(9;22), t(8;14) & More
Hemostasis: Primary vs Secondary & Platelet Plug
Hemostasis for clinical practice: primary platelet plug vs secondary fibrin clot, von Willebrand factor, the platelet steps, and how each is tested, in an interactive walkthrough.
Lymphomas: read the lineage before the label
Lymphomas for clinical practice: Hodgkin with Reed-Sternberg cells vs the non-Hodgkin subtypes, the spread pattern, and the key associations, in an interactive comparison.