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Internal Medicine

The final boss of the shelf. Cardio, pulm, GI, heme, renal, endo, neuro, rheum: every system you swore was its own subject, wearing one coat. Every Bone Wizardry deep-dive here, mapped by clinical system and stacked by how much it actually shows up.

Across every system, the exam keeps testing the same physician tasks: History & Physical / Diagnosis (25-30%), Diagnostic Technologies (25-30%), Management (20-30%), Health Promotion & Prevention (5-10%), and Scientific Mechanisms (10-20%). The pages below cover all five; jump to Read the Test for the diagnostic-technologies rail.

New Module Prevention & Screening USPSTF cancer screening, adult immunizations, and health maintenance by age: the prevention questions that actually show up.
01

Cardiovascular & Circulatory

Yield 16-22%
Heart MurmursFree
Cardio · Valvular
Mitral RegurgitationPro
Cardio · Valvular
Diastolic RumblePro
Cardio · Valvular
Wide S2 SplitPro
Cardio · Heart sounds
Paradoxical S2 SplitPro
Cardio · Heart sounds
CardiomyopathiesFree
Cardio · Myocardial
Frank-Starling MechanismFree
Cardio · Mechanism
HemodynamicsPro
Cardio · Mechanism
Inferior MI + AV BlockPro
Cardio · ACS
Post-MI Complications TimelinePro
Cardio · ACS
MI ED Meds: MONA-BAHPro
Cardio · ACS management
AntiarrhythmicsFree
Cardio · Arrhythmia mgmt
Lead I EKGPro
Cardio · Dx tech
Beta-BlockersPro
Pharm · HTN / IHD mgmt
DigoxinFree
Pharm · Rate / CHF mgmt
Renal Artery Stenosis & RAASFree
Renal · Secondary HTN
Cholesterol Synthesis & RegulationPro
Biochem · Hyperlipidemia
HypertensionPro
Cardio · HTN management
Heart FailureFree
Cardio · HFrEF / GDMT
Atrial FibrillationPro
Cardio · Arrhythmia
Infective EndocarditisPro
Cardio · Valve infection
EKG InterpretationFree
Cardio · Dx tech
Congenital Heart DefectsFree
Cardio · Congenital
Chronic Venous InsufficiencyPro
Cardio · Vascular
02

Respiratory

Yield 16-22%
Asthma vs COPDFree
Resp · Obstructive
PneumoniasFree
Resp · Infection
Lung AbscessFree
Resp · Infection
PE & DVTFree
Resp · Vascular
ARDSFree
Resp · Critical care
Acid-Base & ABGsFree
Resp · Dx tech
Pulm Physiology HubFree
Resp · Mechanism
SarcoidosisFree
Resp · Interstitial
Lung CancersFree
Resp · Oncology
03

Heme / Onc / Immunology

Yield 13-18%
AnemiasFree
Heme · Hub
Microcytic AnemiasFree
Heme · Anemia
Macrocytic / Normocytic & PNHFree
Heme · Anemia
Iron Deficiency WorkupFree
Heme · Dx tech
Lead PoisoningFree
Heme · Toxic
Coagulation & Bleeding DisordersFree
Heme · Coagulation
Coagulation CascadeFree
Heme · Mechanism
Hemophilia & Coag CascadePro
Heme · Coagulation
Platelet DisordersPro
Heme · Coagulation
Drugs of the Clotting CascadePro
Heme · Management
Multiple Myeloma & MGUSFree
Heme · Malignancy
Chromosomal TranslocationsFree
Heme · Malignancy
Hypersensitivity I-IVFree
Immuno · Allergy
Autoantibodies & Drug-Induced LupusFree
Immuno · Dx tech
Primary ImmunodeficiencyPro
Immuno · Immunodeficiency
VasculitidesPro
Immuno · Vasculitis
Opportunistic Infections · CD4 LadderFree
Micro · HIV / AIDS
HIV: Diagnosis & ARTPro
ID · HIV
Sepsis & Septic ShockPro
ID · Critical care
MeningitisFree
ID · CNS infection
Antimetabolites & Drug InteractionsFree
Pharm · Chemo
Cancer PathologyFree
Path · Neoplasm
Where Cancer LandsFree
Path · Metastasis
Oncogenes & Tumor SuppressorsFree
Path · Mechanism
The Psammoma ClubFree
Path · Solid tumor
The Cancer CascadeFree
Path · Radiation
04

GI & Nutrition

Yield 12-16%
Crohn's vs UCFree
GI · IBD
Hepatitis SerologiesFree
GI · Liver / Dx tech
The Liver's Hit List (HCC)Free
GI · Liver
Liver MetastasesFree
GI · Liver
PSC vs PBCFree
GI · Biliary
Pancreas Eats ItselfFree
GI · Pancreas
PPI-Induced HypergastrinemiaPro
GI · Upper GI
Zinc DeficiencyPro
GI · Nutrition
Wernicke + KorsakoffPro
Neuro · Thiamine deficiency
GERD, PUD & H. pyloriPro
GI · Upper GI
Cirrhosis & ComplicationsPro
GI · Liver
05

Nervous System & Mental Health

Yield 8-12%
Stroke SyndromesFree
Neuro · Stroke
Cortical Stroke SyndromesPro
Neuro · Stroke
Brainstem Stroke SyndromesPro
Neuro · Stroke
Lenticulostriate StrokesPro
Neuro · Stroke
Intracranial HemorrhagesPro
Neuro · Stroke
DementiasFree
Neuro · Neurodegenerative
Parkinson DiseasePro
Neuro · Neurodegenerative
Movement DisordersPro
Neuro · Movement
Demyelinating DiseasesFree
Neuro · Demyelinating
NMJ DisordersFree
Neuro · Neuromuscular
Spinal StenosisPro
Neuro · Spinal cord
Seizures & EpilepsyPro
Neuro · Cerebral
Idiopathic Intracranial HypertensionPro
Neuro · Cerebral
Cranial Nerve LesionsFree
Neuro · Peripheral
Schizophrenia & Mood DisordersFree
Psych · Mental health
The Mood Map: AntidepressantsFree
Psych · Management
Antipsychotics, Mood Stabilizers & AnxiolyticsFree
Psych · Management
Cluster A Personality DisordersFree
Psych · Mental health
Code Gray: The Agitated PatientFree
Psych · Management
06

Genitourinary / Renal

Yield 5-10%
AKI vs CKDFree
Renal · AKI / CKD
Nephrotic vs NephriticFree
Renal · Glomerular
RTA Deep DiveFree
Renal · Tubular
Electrolyte DisordersFree
Renal · Fluid / lytes
Renal Artery Stenosis & RAASFree
Renal · Vascular
Diuretic Sites & ToxicityPro
Renal · Management
Prostate Cancer DrugsFree
Pharm · GU oncology
07

Endocrine & Metabolism

Yield 5-7%
DKA vs HHSFree
Endo · Diabetes
Insulinoma & Hypoglycemia WorkupFree
Endo · Diabetes
Antidiabetic Drug ClassesPro
Pharm · Management
Thyroid DisordersFree
Endo · Thyroid
Calcium, PTH & Vitamin D AxisFree
Endo · Parathyroid
Adrenal InsufficiencyPro
Endo · Adrenal
Adrenal AdenomasFree
Endo · Adrenal
Congenital Adrenal HyperplasiaFree
Endo · Adrenal
Pituitary Tumors, SIADH & DIFree
Endo · Pituitary
Gigantism (GH Excess)Free
Endo · Pituitary
MEN SyndromesFree
Endo · Tumor syndrome
The Pancreatic VillainsFree
Endo · Islet tumors
GlucagonomaFree
Endo · Islet tumors
Hypothalamic & Pituitary DrugsFree
Pharm · Management
08

MSK & Rheumatology

Yield 5-7%
The Big 5 Autoimmune DiseasesFree
MSK · Inflammatory
The Spondyloarthropathy QuartetPro
MSK · Seronegative
Autoantibodies & Drug-Induced LupusFree
Immuno · Rheum serology
VasculitidesPro
Immuno · Vasculitis
Viscerosomatic ReflexesFree
OMM · Viscerosomatic
Low Back PainFree
OMM · Somatic dysfunction
09

Integumentary

Yield 5-7%
Classic Derm FindingsFree
Derm · Lesions
Skin CancersFree
Derm · Oncology
Actinic KeratosisFree
Derm · Precancer
Hypersensitivity I-IVFree
Immuno · Atopic mechanism
10

Community Health & Prevention

Yield 5-7%
Prevention & ScreeningFree
IM · New module
Sensitivity, Specificity & Study DesignFree
Biostats · Screening principles
Medical Interpreter RulesFree
Biostats · Communication
Medication AdherenceFree
Endo · Behavioral
🔎

Read the Test

Dx Tech 25-30%

Diagnostic Technologies is the single heaviest physician task on the shelf. These pages cut across every system: the EKG, the ABG, the LFTs, the CBC, and the serology that the vignette hands you.

Acid-Base & ABGsFree
Read the ABG
Iron Deficiency WorkupFree
Read the CBC / iron studies
Hepatitis SerologiesFree
Read the serology panel
AutoantibodiesFree
Read the rheum panel
Lead I EKGPro
Read the tracing
Sensitivity, Specificity & Study DesignFree
Interpret the test
DyslipidemiaPro
IM · Statin intensity by risk
Urinary Tract InfectionsPro
IM · Cystitis vs pyelonephritis
OsteoporosisPro
IM · DEXA, FRAX, bisphosphonates
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