What's New

Abdominal and Groin Hernias

Abdominal Aorta and Branches

Abdominal Aortic Aneurysm

Abdominal Aortic Branches in Anatomy and Clinical Decisions

Abetalipoproteinemia: Build the Particle, Find the Block

Acute Pancreatitis

Allergen Immunotherapy and Blocking IgG4

Allergic Rhinitis and Upper Airway Cough Syndrome

Apolipoprotein A-I and HDL Metabolism

Artery of the Ligamentum Teres and Femoral-Head Perfusion

Atrial Fibrillation: Rate Control

Basilar artery occlusion: follow the tissue, preserve the person

Bell Palsy and Facial Localization

Benign Liver Tumors

Benzene marrow toxicity and CBC monitoring

Bismuth, Sucralfate, and Misoprostol

Botulism: Recognize the Pattern, Protect Breathing

Brachial Plexus and Upper Extremity Nerve Injuries

Brainstem Stroke Syndromes: Trace the Pathway, Test the Pattern

Budd-Chiari Syndrome and Portal Vein Thrombosis

Cancer Pathology: Lineage, Spread, and Driver Logic

Carbon Monoxide Poisoning and Brain Injury

Cardiac Myocyte Action Potential

Cardiomyopathies. Shape, tissue and clinical decisions

Rebuilt lesson with 41 practice cases.

Cervical Radiculopathy: Localize Before You Label

Chapman Points

Choanal Atresia and the Neonatal Airway

REBUILT 👶

Cholangiocarcinoma

Chronic mesenteric and colonic ischemia

Chronic Pancreatitis and Exocrine Pancreatic Insufficiency

Chronic Venous Insufficiency

Cirrhosis and Portal Hypertension

Colon polyps: tissue, complete removal and follow-up

Colonic Parasympathetic Supply and Viscerosomatic Reflexes

Colorectal Cancer Molecular Pathways

Colorectal Cancer: Find It, Stage It, Treat It

Complement Deficiencies: Locate the Break and the Overactive Brake

Congenital heart defects through blood flow

Congenital Intestinal Obstruction

Cranial Dysfunction: Axes, Landmarks, and Clinical Limits

Rebuilt lesson with 33 practice cases.

Crohn Disease vs Ulcerative Colitis

Cushing Syndrome: Confirm, Classify, Localize

Cystic Fibrosis

Dementia with Lewy bodies

Demyelinating diseases: localization, timing and treatment

Dermatomes and Root Localization

Digestive Tract Anatomy and Histology

Disseminated Intravascular Coagulation

Diverticular disease: anatomy, inflammation and the next decision

EKG Interpretation

Elder Abuse and Neglect Reporting

Esophagitis and Esophageal Injury

Extraocular Muscles, Gaze and Visual Fields

Factor VII Deficiency and Isolated Prolonged PT

Frank-Starling

Gallstone Ileus

Gastritis and Gastric Cancer

Gastrointestinal angiodysplasia: find the source, explain the recurrence

Gastrointestinal Blood Supply and Innervation

Gastrointestinal Regulatory Substances

Gastrointestinal Secretory Products

GERD, Erosive Esophagitis, and Peptic Ulcer Disease

Glucagonoma Syndrome: NME, Catabolism, and Pancreatic NET Reasoning

Gram Stain Chart: From Appearance to Clinical Decisions

Rebuilt lesson with 44 practice cases.

Guillain-Barre syndrome

H2 receptor antagonists: target, time and the patient

Heart failure through pressure, perfusion and treatment

Rebuilt lesson with 48 practice cases.

Heart murmurs. Timing, pressure and bedside decisions

Hemochromatosis and Iron Overload

Hemodynamics

Hepatic Encephalopathy

Hepatitis serologies: what the result can actually tell you

Hepatocellular carcinoma: the tumor and the liver

Hereditary polyposis: from tissue pattern to prevention

Hirschsprung Disease: From Distal Aganglionosis to Clinical Decisions

Hypothermia and Cutaneous Vasoconstriction

Iliacus Hematoma and Femoral Neuropathy

Immune Cell Lineage: Read the Blood Family Tree

Important Gastrointestinal Ligaments

Inferior gluteal artery

Inguinal Canal: Routes, Layers and Nerves

Innominate Shears, Flares, and Pubic Shears

Intestinal Malrotation and Midgut Volvulus

Intracranial Hemorrhages

Leber hereditary optic neuropathy: central vision, maternal inheritance, uncertain expression

Lipopolysaccharide and Gram-Negative Septic Shock

Liver Metastases and Secondary Tumors

Liver tissue architecture: follow the path, predict the injury

Locations of Gastrointestinal Secretory Cells

Low Back Pain: Clinical Patterns and Osteopathic Reasoning

Lumbar and Pelvic Counterstrain: Landmarks Before Positions

Lymphatics: Fluid, Anatomy, and Safe Technique Selection

Lysosomal storage diseases: follow the stored material

Malabsorption Syndromes

Malaria Prophylaxis in Pregnancy

MASLD and MASH

Maxillary facial pain: from trigeminal neuralgia to cavernous sinus localization

Microscopic Colitis

Mycoplasma pneumoniae Mucositis and RIME

Myofascial Release and the Muscle Stretch Reflex

Necrotizing enterocolitis

Neurodegeneration Decoder: Anatomy, Circuits and Tempo

Normal Gastrointestinal Embryology

Octreotide: suppress the output, treat the cause

OMM Fundamentals: From Examination to Treatment Choice

Opioid Intoxication and Naloxone

Opportunistic infections: connect immune risk to the affected organ

Oral and salivary pathologies: location, time and tissue

Pancreatic Adenocarcinoma

Pancreatic Pseudocyst and Pancreatitis Complications

Pancreatic Secretions and Carbohydrate Absorption

Peripheral Vertigo and BPPV

Pituitary tumors and the logic of water balance

Pneumonias: from airspace findings to targeted care

Porcelain Gallbladder

Portosystemic Anastomoses

Post-MI complications through rhythm, flow, and tissue failure

Posterior Innominate Rotation and Hamstring Dysfunction

PPI-associated hypergastrinemia: read the hormone beside the acid

Pregnancy Biomechanics and Lumbar Lordosis

Primary Sclerosing Cholangitis versus Primary Biliary Cholangitis

Proctitis

Proton pump inhibitors: target, timing and the reason to continue

Proximal Myopathy and Creatine Kinase

Recurrent Lateral Patellar Dislocation

Reye Syndrome

Rib 3-5 Inhalation Dysfunction and Muscle Energy

Right Varicocele and Retroperitoneal Masses

Sarcoidosis: diagnosis, organ risk, and treatment

Schizophrenia and mood disorders

Secondary Biliary Obstruction and Cirrhosis

Secondary Spontaneous Pneumothorax in COPD

Seizures and epilepsy

Solitary Pulmonary Nodules and Lung Cancer Red Flags

Spontaneous bacterial peritonitis: sample, treat and reassess

Subarachnoid Hemorrhage and CSF Findings

Sulfasalazine and 5-Aminosalicylates

Systolic Murmur Localizer

T-Cell Costimulation, Immune Tolerance and Checkpoints

Tension pneumothorax

The Pectinate Line

The TCA Cycle: Acceptor Pools, Electron Yield, and Disease

Thoracic Somatic Dysfunction

Thoracic Type II Somatic Dysfunction

Tracheoesophageal Anomalies

Trazodone, priapism, and the venous outlet

Upper and Lower Extremity Findings: Anatomy, Autonomics and Manual Medicine

Vasculitis: read the vessel before naming the disease

Ventral Wall Defects

Vincristine neuropathy and vinca toxicities

Wernicke Encephalopathy and Korsakoff Syndrome

Zenker and Meckel diverticula: follow the wall, pressure, and tissue

Zenker Diverticulum and Killian Triangle

September 30, 2026

Celiac Trunk and Foregut Vascular Anatomy

Rebuilt lesson with 48 practice cases.

Clotting cascade: localize the defect, then explain the phenotype

Cortisol physiology: timing, feedback, and stress adaptation

Dyslipidemia and Lipid Management

Free Radicals and the Phagocyte Respiratory Burst

Glycolysis and Gluconeogenesis: Carbon, Redox, and Clinical Decisions

Insulinoma and the hypoglycemia critical sample

Ionizing radiation: from energy deposition to cancer

Lymphomas: read the lineage before the label

Olfactory Nerve and Cribriform Plate

Oncogenes and tumor suppressors: added drive versus lost restraint

Osteoporosis: read the fracture, DXA, risk, and treatment sequence

Type 1 vs Type 2 Diabetes: Production, Resistance, and Crisis

Urea cycle: localize the block and protect the brain

September 28, 2026

Acute Cholecystitis and Biliary Disease

Acute Ischemic Stroke Management

Adrenal Insufficiency

AKI and CKD. Read the timeline, perfusion, and urine together

Rebuilt lesson with 39 practice cases.

Alcohol-Associated Liver Disease

Antibiotics: connect the target to the infection

Antidepressants

Antidiabetic drugs. Match the mechanism to the person

Antiemetics

Antipsychotics, Mood Stabilizers, and Anxiolytics

Anxiety, OCD, and Related Disorders

Rebuilt lesson with 38 practice cases.

Asthma and COPD

Autoimmune Hepatitis

Autonomic failure from standing physiology to treatment choices

Autonomic Spinal Levels: Trace the Pathway Before the Pattern

Rebuilt lesson with 40 practice cases.

Bartholin Cysts and Abscesses

Breast Neoplasms from Finding to Treatment

Rebuilt lesson with 33 practice cases.

Cervical Cancer Screening, HPV and Dysplasia

Cervical OMM

Coagulation: connect assays to bleeding and thrombosis

Contraception

De Quervain Tenosynovitis

Rebuilt lesson with 18 practice cases.

Diuretics and the nephron

DKA and HHS: Ketones, Acidosis, and Hyperosmolality

E. coli and Shigella: mechanism, tissue and treatment

Eating disorders

Ectopic Pregnancy

Electrolytes in clinical context

Glycogen metabolism

Hemolytic anemias: locate the destruction

Inferior MI, right ventricular failure, and AV block

Liver Enzymes, AST/ALT Ratio, and Synthetic Function

Lumbar Dysfunctions: From Palpatory Findings to a Coherent Diagnosis

Mandibular Trigeminal Neuralgia and Foramen Ovale

Measurement Scales and Ordinal Data

REBUILT 📊

Rebuilt lesson with 16 practice cases.

Nephrotic and nephritic syndromes. Find the injured compartment

Rebuilt lesson with 46 practice cases.

Personality disorders

Piriformis and Deep Gluteal Pain

Preeclampsia Diagnosis and Severe Features

Renal artery stenosis and RAAS

Renal tubular acidosis

Sacral diagnosis from landmarks and motion

Scoliosis

Rebuilt lesson with 48 practice cases.

Stroke Syndromes

The Agitated Patient

The Calcium, PTH, and Vitamin D Axis

Thyroid disorders from hormone source to treatment

TORCH and other perinatal infections: anatomy, timing and action

Rebuilt lesson with 29 practice cases.

Vitamin and Mineral Absorption

Zink Patterns

September 27, 2026

Achalasia and Esophageal Motility Disorders

Actinic keratosis and the epidermal boundary

Acute Appendicitis

Acute Mesenteric Ischemia

Alpha-1 Antitrypsin Deficiency Liver Disease

Anticonstipation Drugs

Antidiarrheal Drugs

Barrett Esophagus and Esophageal Cancer

Calcium Nephrolithiasis and Sodium Intake

Complement: surfaces, amplification and protection

Cortical Stroke Syndromes: Localize the Dysfunction

Fungi and parasites: transmission routes, tissue forms and treatment decisions

Rebuilt lesson with 42 practice cases.

Gabapentinoids: Target, Exposure and Clinical Decisions

Glycogen storage diseases

Headaches

Interferons: signal, response and antiviral defense

Irritable bowel syndrome: understand the pattern, choose the target

Leptin Physiology and Obesity Resistance

Lynch syndrome: from tumor testing to family prevention

Maple syrup urine disease and the blocked metabolic step

Menopause Hormone Patterns

Pancreas and Spleen Embryology

Pentose phosphate pathway

Petrous Temporal Fracture and the Lesser Petrosal Nerve

Pregnancy physiology: what changes, and why

Primary amenorrhea: locate the problem and choose the next step

Retroperitoneal structures: follow the lining

Rib mechanics and respiratory dysfunction

Sexual differentiation: anatomy, hormones, and response

Skin cancers through tissue, invasion and risk

Small intestinal bacterial overgrowth: from stasis to a defensible diagnosis

Sodium and Osmolality: Follow the Water

Somatic Symptoms, Health Anxiety and Functional Neurologic Disorder

Staphylococci, streptococci and enterococci: tests that change care

Trauma and PTSD Disorders: Criteria, Context and Care

Drug-induced kidney injury

September 23, 2026

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IgA nephropathy. From urinary findings to kidney protection

Nephrolithiasis: protect drainage, explain the chemistry

Screening Tests, Predictive Values, and Study Results

REBUILT 📊

Rebuilt lesson with 41 practice cases.

Ureter Blood Supply: Preserve the Connections

Urinary Tract Infections

September 21, 2026

ARDS and the lung that needs protection

PE and DVT from probability to treatment

September 20, 2026

Enzymes, inhibition and energy metabolism

Foscarnet | Activation, resistance and electrolyte safety

Rebuilt lesson with 18 practice cases.

Glucocorticoids and fragile bone

Rebuilt lesson with 18 practice cases.

Muscle Contraction Types

Alpha blockers: receptor to bedside

September 18, 2026

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Beta blockers: predict the tissue response

Chiari malformations and syringomyelia

Galactose and fructose. Follow the sugar, predict the consequence

Hemoglobin: binding, release, and oxygen delivery

PKU: follow the blocked pathway

Pulmonary Physiology: Air, Blood and Pressure

Sciatica Localizer: Root, Nerve, Plexus, or Canal?

Spinal Cord Tracts and Syndromes

September 17, 2026

Bowel and Gastric Volvulus

Dubin-Johnson and Rotor Syndromes

Rebuilt lesson with 15 practice cases.

Duct Stones and Acute Cholangitis

Gallstones and Biliary Colic

Gilbert and Crigler-Najjar Syndromes

Ileus and Colonic Pseudo-Obstruction

Intussusception

Jaundice: Build the Differential

Neonatal Hyperbilirubinemia

Neuromuscular Junction Disorders: MG, LEMS and Botulism

Rebuilt lesson with 33 practice cases.

Small-Bowel Obstruction

Medical Interpreter Rules and Meaningful Communication

September 16, 2026

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Meningitis: urgent decisions, CSF patterns and pathogen-specific care

Pneumococcus and acute otitis media: the organism, the ear and the treatment decision

September 15, 2026

Maxillary dental nerves

September 9, 2026

Anemias: explain cell size and marrow response

Cranial nerves and clinical localization

Rebuilt lesson with 39 practice cases.

Platelet disorders: number, function and clinical pattern

Rebuilt lesson with 39 practice cases.

Toxidromes and antidotes: recognize the failing physiology

Rebuilt lesson with 35 practice cases.

REBUILT

August 25, 2026

Atrial Fibrillation: Rate Control

Corrected pre-excited atrial fibrillation treatment and clarified when stability changes the next step.

Corrected the urinary nitrite mechanism to bacterial nitrate-to-nitrite reduction.

Chapman Points

Reworked mixed acidosis reasoning using delta-delta and the hyperchloremic NAGMA component.

Acid-base disorders

Secondary Spontaneous Pneumothorax in COPD

August 17, 2026

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Recognize secondary spontaneous pneumothorax in COPD, differentiate tension from simple leak, and choose needle decompression, chest tube, or definitive pleurodesis.

Psoas Syndrome and Iliopsoas Dysfunction

Recognize a coherent iliopsoas dysfunction pattern, choose direct or indirect treatment, and stop when red flags suggest infection, bleeding, or nerve injury.

Apolipoprotein A-I and HDL Metabolism

Trace ApoA-I, ABCA1, LCAT, CETP, and SR-BI through HDL maturation and reverse cholesterol transport.

Rib 3-5 Inhalation Dysfunction and Muscle Energy

Map pump-handle ribs 2 to 5, find the lowest key rib of an inhaled group, and run direct muscle energy toward the exhalation barrier.

Menopause Hormone Patterns

Understand follicle depletion, FSH and estradiol patterns, clinical diagnosis, POI and amenorrhea mimics, symptoms, bone effects, and hormone-therapy principles

Pregnancy Biomechanics and Lumbar Lordosis

Explain center-of-mass and lordosis changes without reducing all pregnancy pain to posture, and recognize positioning, neurologic, and obstetric red flags.

Lipopolysaccharide and Gram-Negative Septic Shock

Trace the pathway from gram-negative bacterial LPS release through TLR4-MD2 activation, cytokine cascade, vasoplegia, and distributive shock, then apply the

Right Varicocele and Retroperitoneal Masses

Use gonadal venous anatomy, standing and supine examination, Doppler reflux, suspicious right-sided features, targeted abdominal imaging, and fertility indicati

Leptin Physiology and Obesity Resistance

Trace leptin from adipocyte to hypothalamus, contrast deficiency with resistance, and explain why replacement treats rare low-leptin states rather than common o

Factor VII Deficiency and Isolated Prolonged PT

Use isolated PT prolongation, mixing studies, factor VII activity, bleeding history, and acquired-cause assessment to diagnose factor VII deficiency.

Proximal Myopathy and Creatine Kinase

Localize proximal weakness, interpret CK, distinguish inflammatory, toxic, endocrine, steroid, neurologic, and neuromuscular-junction mimics.

Carbon Monoxide Poisoning and Brain Injury

Recognize carbon monoxide poisoning, use carboxyhemoglobin and clinical findings to guide treatment, and apply hyperbaric oxygen for delayed neurologic sequelae.

Preeclampsia Diagnosis and Severe Features

Diagnose preeclampsia, identify severe features and HELLP, stabilize severe hypertension, use magnesium appropriately, and plan delivery.

Dementia with Lewy bodies

Distinguish DLB from Alzheimer and Parkinson disease dementia using core clinical features: fluctuating cognition, visual hallucinations, parkinsonism, and RBD.

NEW 📊

Measurement Scales and Ordinal Data

Classify nominal, ordinal, interval, and ratio data; interpret Likert items; choose summaries and tests without inventing quantitative meaning.

Disseminated Intravascular Coagulation

Recognize DIC from its trigger, evolving laboratory pattern, bleeding-thrombosis phenotype, and source-directed management.

Hypothermia and Cutaneous Vasoconstriction

Understand the thermoregulatory response to hypothermia including cutaneous vasoconstriction, shivering, and the transition from heat conservation to failure.

Opioid Intoxication and Naloxone

Recognize opioid intoxication by the classic triad of respiratory depression, miosis, and CNS depression, then reverse it with naloxone while anticipating

Maxillary facial pain: from trigeminal neuralgia to cavernous sinus localization

Trace V2 through the cavernous sinus and foramen rotundum, distinguish classic neuralgia from mimics, and recognize urgent multi-nerve syndromes.

Benzene marrow toxicity and CBC monitoring

Connect chronic benzene exposure to cytopenias, aplastic marrow, MDS and AML, then interpret CBC surveillance correctly.

Mandibular Trigeminal Neuralgia and Foramen Ovale

Separate classic V3 trigeminal neuralgia from foramen ovale neuropathy using attack phenotype, lower-face sensation, and masticatory motor findings.

Iliacus Hematoma and Femoral Neuropathy

Localize femoral neuropathy from iliacus hematoma, distinguish bleeding instability from neurologic progression, and avoid one universal decompression rule.

Mean Arterial Pressure and Total Peripheral Resistance

Understand how mean arterial pressure is determined by cardiac output and systemic vascular resistance and recognize clinical states that alter each independently.

Colonic Parasympathetic Supply and Viscerosomatic Reflexes

Map colonic parasympathetic supply, explain viscerosomatic facilitation, distinguish autonomic territory from spinal findings, and keep OMT adjunctive to medica

Elder Abuse and Neglect Reporting

Recognize elder abuse and neglect, interview privately, document objectively, assess capacity and immediate danger, and follow jurisdiction-specific reporting d

Petrous Temporal Fracture and the Lesser Petrosal Nerve

Prioritize temporal bone trauma complications, trace CN IX through the lesser petrosal nerve, and preserve the common exit route plus its variants.

Allergen Immunotherapy and Blocking IgG4

Learn how allergen immunotherapy induces IgG4 blocking antibodies to outcompete IgE, promote Treg expansion, and establish clinical tolerance in allergic disease.

Gabapentinoids: Target, Exposure and Clinical Decisions

Gabapentin and pregabalin bind alpha-2-delta calcium channel subunits, reducing neurotransmitter release in neuropathic pain, seizures, and fibromyalgia.

NEW 🍽️

Zenker Diverticulum and Killian Triangle

Localize Zenker diverticulum to Killian triangle, recognize regurgitation and aspiration, use barium swallow safely, and compare myotomy options.

Leber hereditary optic neuropathy: central vision, maternal inheritance, uncertain expression

Recognize LHON, its maternal mitochondrial inheritance, complex I mutations, penetrance, testing, and key mimics.

Myofascial Release and the Muscle Stretch Reflex

Distinguish direct and indirect myofascial release from muscle energy, trace the stretch reflex, and avoid unsupported claims of permanent neural resetting.

Choanal Atresia and the Neonatal Airway

Recognize bilateral and unilateral choanal atresia, stabilize the neonatal airway, confirm anatomy, screen CHARGE, and plan endoscopic repair.

Pneumonic plague presents with hemoptysis and rapid progression. Learn Yersinia pestis virulence, antibiotic selection, and post-exposure prophylaxis.

Pneumonic Plague

Thoracic Type II Somatic Dysfunction

Diagnose thoracic Type II somatic dysfunction and set up direct muscle energy by separating ease from the restrictive barrier.

Recurrent Lateral Patellar Dislocation

Recognize acute patellar-dislocation injuries, map recurrence risk factors, and use anatomy plus uncertain comparative evidence to guide long-term planning.

Trazodone, priapism, and the venous outlet

Trazodone metabolite m-CPP blocks alpha-1 receptors in the corpus cavernosum, preventing detumescence and causing ischemic priapism requiring emergency aspiration.

Subarachnoid Hemorrhage and CSF Findings

Recognize aneurysmal SAH, interpret CT and CSF xanthochromia, grade severity, initiate nimodipine, aneurysm securement, and prevent complications.

Calcium Nephrolithiasis and Sodium Intake

Connect sodium intake to hypercalciuria, preserve normal dietary calcium, interpret 24-hour urine, and prevent recurrent calcium stones safely.

Allergic Rhinitis and Upper Airway Cough Syndrome

Distinguish allergic rhinitis from nonallergic rhinitis as causes of upper airway cough syndrome using nasal symptoms, triggers, exam findings, allergy testing,

Malaria Prophylaxis in Pregnancy

Select malaria chemoprophylaxis in pregnancy by trimester, drug safety, region resistance patterns, and Plasmodium species.

Posterior Innominate Rotation and Hamstring Dysfunction

Diagnose posterior innominate rotation, distinguish superior shear, and connect hamstring mechanics to a direct muscle-energy setup.

Mycoplasma pneumoniae Mucositis and RIME

Recognize Mycoplasma-associated RIME and distinguish it from erythema multiforme and drug-triggered SJS/TEN.

Basilar artery occlusion: follow the tissue, preserve the person

Recognize basilar artery occlusion syndromes from prodromal symptoms to locked-in syndrome and differentiate top-of-the-basilar, midbasilar, and distal patterns.

Solitary Pulmonary Nodules and Lung Cancer Red Flags

Evaluate solitary pulmonary nodules by size, density, growth, and risk to classify malignancy probability and choose between surveillance, biopsy, or resection.

Vincristine neuropathy and vinca toxicities

Vincristine causes a length-dependent sensorimotor and autonomic neuropathy through axonal microtubule destruction.

De Quervain Tenosynovitis

Localize De Quervain disease, distinguish staged Finkelstein testing from Eichhoff, and use evidence-supported nonoperative care before surgery.

NEW

August 9, 2026

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Lower Extremity Nerve Injuries: Localize by Function

Master lower extremity nerve injuries for clinical practice: sciatic, common peroneal, femoral, tibial, superior gluteal, and lateral femoral cutaneous nerve, with animated anatomy, interactive vignettes, and Chicago-style explanations.

Thoracic Outlet Syndrome: Neurogenic, Venous & Arterial

Thoracic outlet syndrome board review: neurogenic, venous, and arterial TOS with anatomy, provocative tests, and danger mimics.

Seronegative Spondyloarthropathies: The 4 Compared

The spondyloarthropathy quartet: ankylosing spondylitis, psoriatic, reactive, and IBD-arthritis compared by enthesitis mechanism, HLA-B27 link, and imaging.

Spondylitis, Spondylosis, Spondylolysis & Spondylolisthesis

Spondylitis, spondylosis, spondylolysis, spondylolisthesis: decode the four suffix mechanisms, read the Scottie dog, and split inflammatory from mechanical pain.

Scoliosis description and naming: convexity rule, rib hump, Adams test, Cobb angle staging, Risser, and red flags that make a curve non-idiopathic.

Scoliosis

Rotator Cuff Disease and Subacromial Impingement

Rotator cuff disease and subacromial impingement: the SITS muscles, the special tests, the 60-120 degree painful arc, and impingement versus full-thickness tear.

Forearm Flexors & FDS Injury

Forearm flexors and FDS vs FDP injury: the two-tendon rule, Camper

The Big 5 Autoimmune Diseases

Antibody fingerprints for the big 5 autoimmune diseases: SLE, RA, scleroderma, dermatomyositis, and Sjogren

Rib mechanics and respiratory dysfunction

August 8, 2026

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Learn inhalation and exhalation rib dysfunction, pump and bucket mechanics, key ribs, posterior contact points, and HVLA thrust directions for boards.

Centriacinar vs Panacinar Emphysema

Compare centrilobular and panacinar emphysema by acinar involvement, lobar distribution, cause, and the stem clues that separate them on board questions.

Asthma vs COPD for clinical practice: reversible vs fixed obstruction, the PFT pattern, the inflammatory cells, and the treatment ladder for each, in an interactive comparison.

August 1, 2026

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Asthma and COPD

Pregnancy physiology: what changes, and why

Pregnancy physiology for clinical practice: the cardiovascular, respiratory, renal, and hematologic adaptations, dilutional anemia, and hormone changes, fully interactive.

Psammoma Bodies: The 5 Classic Tumors

Psammoma bodies for clinical practice: the laminated calcifications and the tumors that show them, papillary thyroid, serous ovarian, meningioma, and more, fully interactive.

Oncogenes and tumor suppressors: added drive versus lost restraint

Cancer genetics for clinical practice: oncogene gain-of-function vs tumor suppressor loss, the two-hit hypothesis, and the high-yield genes, fully interactive.

Name and classify scoliosis for Medical Education: convexity naming, Cobb angle, rib hump on Adams forward bend, and rotation mechanics, with interactive spine diagrams.

Scoliosis

Low Back Pain: Clinical Patterns and Osteopathic Reasoning

Work up low back pain for Medical Education: red flags, cauda equina, mechanical vs serious causes, and the osteopathic structural exam with OMT, fully interactive.

Fryette's Principles: From Examination to Direction

Master Fryette

Extraocular Muscles, Gaze and Visual Fields

Eye movement localization for clinical practice: six extraocular muscles, CN III/IV/VI palsies, visual field cuts, INO, PPRF, FEF, one-and-a-half syndrome, and board-style vignettes.

CNS Embryology: From Tissue Origins to Clinical Anatomy

CNS development for clinical practice: neural tube vs neural crest derivatives, the brain vesicles, and where every structure comes from, in one interactive embryology map.

Cerebral Cortex: Brodmann Areas, Lobes, Aphasias & Visual Fields

Cerebral cortex localization for clinical practice: Brodmann areas, motor homunculus, FEF lesions, Broca and Wernicke aphasia, parietal neglect, optic radiations, Kluver-Bucy, and macular sparing.

Chiari malformations and syringomyelia

Chiari malformations for clinical practice: Type I tonsillar herniation vs Type II with myelomeningocele and syringomyelia, with interactive posterior fossa anatomy and vignettes.

Staphylococci, streptococci and enterococci: tests that change care

Staph vs Strep for clinical practice: the catalase and coagulase tests, hemolysis patterns, and the disease each species causes, in an interactive identification tree.

Meningitis: urgent decisions, CSF patterns and pathogen-specific care

Meningitis for clinical practice: the bacterial, viral, and fungal CSF patterns, the top organisms by age, and empiric treatment, in an interactive CSF interpretation grid.

E. coli and Shigella: mechanism, tissue and treatment

E. coli vs Shigella for clinical practice: the diarrhea types, Shiga toxin and HUS, EHEC O157:H7, and the lab differences, in an interactive comparison built for the exam.

UPDATED 🛡️

Autoantibodies: Disease Associations & Drug-Induced Lupus

Autoantibodies for clinical practice: ANA, anti-dsDNA, anti-Smith, anti-histone, RF, anti-CCP, and the diseases each marks, in an interactive antibody-to-disease map.

Platelet disorders: number, function and clinical pattern

Platelet disorders for clinical practice: ITP, TTP, HUS, and von Willebrand disease, separated by platelet count, schistocytes, and ADAMTS13, in an interactive comparison.

Cancer Translocations: t(9;22), t(8;14) & More

High-yield oncology translocations for clinical practice: Philadelphia t9;22, Burkitt t8;14, APL t15;17, follicular t14;18, and the gene each activates, in an interactive table.

Pancreatic Neuroendocrine Tumors: VIPoma & Friends

Pancreatic neuroendocrine tumors for clinical practice: insulinoma, gastrinoma, glucagonoma, VIPoma, and somatostatinoma, each by its hormone syndrome, in an interactive lineup.

MEN Syndromes: MEN1 vs MEN2A vs MEN2B

MEN syndromes for clinical practice: MEN1, MEN2A, and MEN2B, the RET mutation, medullary thyroid cancer, and pheochromocytoma, in an interactive comparison.

Squamous lung carcinoma: tissue, calcium and local anatomy

Squamous cell lung carcinoma: central location, smoking, keratin pearls and intercellular bridges, and PTHrP-driven hypercalcemia, with interactive pathology.

Varicocele: Dilation of the Pampiniform Plexus

Varicocele for clinical practice: the dilated pampiniform plexus, the left-sided bag of worms, the renal vein drainage reason, and the infertility link, with interactive anatomy.

Umbilical Cord Vessels: Two Arteries, One Vein

Umbilical cord vessels for clinical practice: two arteries carrying deoxygenated blood and one vein carrying oxygenated, the single-artery association, with interactive fetal circulation.

Placenta accreta spectrum: when the separation interface fails

Placenta accreta for clinical practice: the defective decidual layer, abnormal villous adherence, prior C-section risk, and postpartum hemorrhage, with interactive obstetric pathology.

Breast Neoplasms from Finding to Treatment

Breast neoplasms for the boards. Fibroadenoma, fibrocystic change, ductal vs lobular carcinoma, Paget disease, and receptor status, in an interactive comparison.

IgA nephropathy. From urinary findings to kidney protection

IgA nephropathy for clinical practice: Berger disease, gross hematuria within days of a URI, mesangial IgA deposits, and the prognosis, with interactive renal pathology.

Drug-induced kidney injury

Nephrotoxic drugs for clinical practice: aminoglycosides and contrast causing ATN, the drugs causing interstitial nephritis, and the urinalysis clues, fully interactive.

Grief vs Major Depression: Where to Draw the Line

Grief vs MDD for clinical practice: normal bereavement vs major depressive disorder, the duration and feature differences, and the SIG E CAPS criteria, in an interactive comparison.

Statins and Bile Acid Sequestrants

Lipid-lowering drugs for clinical practice: statins inhibiting HMG-CoA reductase vs bile acid sequestrants, their LDL effects, and key toxicities like myopathy, fully interactive.

Tanner Staging: All 5 Stages of Puberty

Puberty for clinical practice: the Tanner stages, the order of pubertal events in girls and boys, the growth spurt timing, and precocious vs delayed puberty, fully interactive.

Neuroblastoma: N-myc & Dancing Eyes

Neuroblastoma for clinical practice: the adrenal medulla tumor in young children, elevated HVA and VMA, N-myc amplification, and opsoclonus-myoclonus, fully interactive.

Xeroderma Pigmentosum: Failed NER & Skin Cancer

Xeroderma pigmentosum for clinical practice: the defective nucleotide excision repair, extreme UV sensitivity, early skin cancers, and the thymine dimer problem, fully interactive.

Thoracic Somatic Dysfunction

Diagnose thoracic somatic dysfunction for the boards. Type 1 group curves vs Type 2 single segments, ERS and FRS naming, and rib relationships, with interactive drills.

Understand muscle energy for the boards. Isometric, isotonic, and isolytic contractions, post-isometric relaxation, and how MET resets the barrier, fully interactive.

Muscle Contraction Types

HVLA principles: judge the tissue before the thrust

Master high velocity low amplitude OMT for the boards. Indications, absolute contraindications, localization to the barrier, and the thrust, with interactive drills.

Pilocytic Astrocytoma: Rosenthal Fibers

Pilocytic astrocytoma for clinical practice: most common pediatric brain tumor, cerebellum, cystic with mural nodule, Rosenthal fibers, and GFAP, interactive and vignette-driven.

Phakomatoses: Neurocutaneous Syndromes Compared

The phakomatoses for clinical practice: NF1, NF2, tuberous sclerosis, Sturge-Weber, and von Hippel-Lindau, with the skin plus tumor clue for each in an interactive grid.

Olfactory Nerve and Cribriform Plate

The olfactory nerve for clinical practice: cribriform plate fracture, anosmia, CSF rhinorrhea, and how smell fibers cross the sieve, with interactive anterior fossa anatomy.

Neurofibromatosis Type 2: Bilateral Schwannomas

NF2 for clinical practice: bilateral vestibular schwannomas, meningiomas, ependymomas, chromosome 22, and how it differs from NF1, with interactive anatomy and vignettes.

Neurofibromatosis Type 1: Cafe-au-Lait & Lisch

NF1 for clinical practice: cafe-au-lait spots, Lisch nodules, neurofibromas, optic glioma, chromosome 17, and autosomal dominant inheritance, with interactive findings and vignettes.

Spinal Tracts: DCML vs Spinothalamic vs Corticospinal

The long tracts for clinical practice: dorsal columns, spinothalamic, and corticospinal, where each decussates, and the deficit a lesion gives, in an interactive cord cross-section.

Medulloblastoma: Cerebellar PNET in Kids

Medulloblastoma for clinical practice: cerebellar vermis, small blue cells, Homer-Wright rosettes, drop metastases, and hydrocephalus in children, interactive and vignette-led.

Huntington Disease, CAG Repeats & Chorea

Huntington disease for clinical practice: CAG trinucleotide repeats, anticipation, caudate atrophy, chorea, and decreased GABA and ACh, with interactive genetics and vignettes.

Femoral Nerve & Hip Flexor Spasticity

Femoral nerve and hip flexors for clinical practice: motor and sensory territory, spasticity patterns, and lesion localization, with interactive lower-limb innervation maps.

Ependymoma, Fourth Ventricle Tumor

Ependymoma for clinical practice: fourth ventricle location, perivascular pseudorosettes, hydrocephalus in children, and the prognosis, with interactive pathology and vignettes.

Cribriform Plate & CN I, Anosmia from Trauma

Olfactory nerve and crista galli for clinical practice: cribriform plate fracture, anosmia, and CSF rhinorrhea, with the anterior cranial fossa anatomy made interactive.

Craniopharyngioma: anatomy, hormones and function

Craniopharyngioma for clinical practice: Rathke pouch origin, calcified suprasellar mass, bitemporal hemianopia, and motor oil cyst fluid, with interactive pathology and vignettes.

ALS, Upper + Lower Motor Neuron Signs

Amyotrophic lateral sclerosis for clinical practice: combined UMN and LMN signs with no sensory loss, SOD1, anterior horn plus corticospinal tracts, interactive and vignette-driven.

AIDS Dementia Complex, HIV Encephalopathy

HIV-associated dementia for clinical practice: microglial nodules, multinucleated giant cells, subcortical pattern, and CD4 threshold, with interactive pathology and vignettes.

4 Dopamine Pathways, Antipsychotic Effects

The four dopamine pathways for clinical practice: mesolimbic, mesocortical, nigrostriatal, and tuberoinfundibular, and how antipsychotics hit each, in an interactive circuit.

Sepsis and Septic Shock · Hour-1 Bundle and Shock Physiology

Sepsis and septic shock on the medicine shelf: Sepsis-3 definitions, the Hour-1 bundle, qSOFA, norepinephrine, distributive shock, and source control, with original clinical vignettes.

Pneumococcus and acute otitis media: the organism, the ear and the treatment decision

Acute otitis media for clinical practice: S. pneumoniae as the top cause, the bulging erythematous tympanic membrane, the other organisms, and treatment, fully interactive.

HIV Diagnosis and Antiretroviral Management

HIV diagnosis and antiretroviral management for clinical practice: fourth-generation testing algorithm, acute retroviral syndrome, ART for everyone, PrEP, PEP, IRIS, and CD4 prophylaxis thresholds.

Group B Strep Across the Lifespan · Newborns and Diabetic Adults

Group B Streptococcus is not only a newborn bug. Learn neonatal early vs late onset, the lab lineup, and why diabetes makes it a real cause of invasive disease in adults.

Fungi and parasites: transmission routes, tissue forms and treatment decisions

Fungi and parasites for clinical practice: the systemic and opportunistic fungi plus the board-heavy protozoa, nematodes, cestodes, and trematodes, each by its exposure, clue, and treatment.

Lymphomas: read the lineage before the label

Lymphomas for clinical practice: Hodgkin with Reed-Sternberg cells vs the non-Hodgkin subtypes, the spread pattern, and the key associations, in an interactive comparison.

Hemostasis: Primary vs Secondary & Platelet Plug

Hemostasis for clinical practice: primary platelet plug vs secondary fibrin clot, von Willebrand factor, the platelet steps, and how each is tested, in an interactive walkthrough.

Type 1 vs Type 2 Diabetes: Production, Resistance, and Crisis

Diabetes for clinical practice: autoimmune type 1 vs insulin-resistant type 2, the antibodies, C-peptide, diagnostic criteria, and complications, in an interactive comparison.

Pheochromocytoma and paraganglioma: follow the catecholamine signal

Pheochromocytoma for clinical practice: the catecholamine surges, episodic hypertension and the 5 Ps, plasma metanephrines, and alpha-before-beta blockade, fully interactive.

Jod-Basedow: Iodine, Autonomy, and Thyroid Hormone Synthesis

Jod-Basedow for clinical practice: how an iodine load triggers hyperthyroidism in nodular goiter, contrasted with the Wolff-Chaikoff effect, with interactive thyroid physiology.

Cushing Syndrome: Confirm, Classify, Localize

Cushing syndrome for clinical practice: ACTH-dependent vs independent, the dexamethasone suppression tests, and the clinical signs, fully interactive.

Cortisol physiology: timing, feedback, and stress adaptation

Cortisol for clinical practice: the HPA axis, the diurnal rhythm, and cortisol

Infective Endocarditis: Vegetations, Duke Criteria & the Peripheral Signs

Infective endocarditis for clinical practice: fever plus new murmur, the organism-to-risk-factor map, acute versus subacute, Janeway versus Osler, the modified Duke criteria, blood cultures then echo, and when to operate.

Hypertension: Staging, First-Line Drugs, and the Crisis Rule

Hypertension for clinical practice: ACC/AHA staging, when to start drugs, first-line classes and compelling indications, and hypertensive emergency vs urgency, in an interactive guide built for the exam.

Congenital heart defects through blood flow

Congenital heart defects for clinical practice: the 5 T cyanotic lesions vs left-to-right shunts, Eisenmenger, and the murmur for each, mapped in an interactive comparison.

Atrial Fibrillation: Rate, Rhythm, and Stroke Prevention

Atrial fibrillation for clinical practice: irregularly irregular pulse with no P waves, stable rate control vs unstable cardioversion, CHA2DS2-VASc stroke risk, DOAC vs warfarin, and the 48-hour cardioversion rule, in an interactive deep-dive built for the exam.

The Five Fates of Pyruvate and Alcohol Metabolism

Pyruvate and ethanol for clinical practice: the five fates of pyruvate, pyruvate dehydrogenase, and how alcohol raises NADH to drive lactate and fat, with an interactive map for Step 1.

Lysosomal storage diseases: follow the stored material

Lysosomal storage diseases for clinical practice: Tay-Sachs, Gaucher, Niemann-Pick, Fabry, Hurler, and Hunter, with the enzyme and clue for each in an interactive grid for Step 1.

The TCA Cycle: Acceptor Pools, Electron Yield, and Disease

The citric acid cycle for clinical practice: each NADH and FADH2 yield, the malate-aspartate and glycerol shuttles, and ATP accounting, with an interactive cycle diagram for Step 1.

Hunter syndrome for clinical practice: X-linked iduronate-2-sulfatase deficiency, mild course, and no corneal clouding vs Hurler, with interactive pathology and board vignettes.

Hunter Syndrome

Glycolysis and Gluconeogenesis: Carbon, Redox, and Clinical Decisions

Glycolysis for clinical practice: the rate-limiting PFK-1 step, regulation, net ATP yield, and key enzyme deficiencies, with an interactive pathway diagram built for Step 1.

Shoulder and Rotator Cuff

Shoulder & Rotator Cuff: SITS muscles, special tests and thoracic outlet syndrome.

Brachial Plexus and Nerve Injuries

Brachial Plexus & Nerve Injuries: plexus anatomy and peripheral nerve injuries of the hand.

Forearm, Dermatomes and OMM

Forearm, Dermatomes & OMM: upper extremity dermatomes and deep tendon reflexes.

Practice Quiz: extremities and ANS board-style questions with explanations.

Practice Quiz

Lower Extremity: knee anatomy, Q angle and alignment for the boards.

Lower Extremity

ANS & Viscerosomatics: sympathetic innervation by organ and the viscerosomatic reflex map.

ANS and Viscerosomatics

OMM: Musculoskeletal and ANS

Musculoskeletal & Autonomic Nervous System: hub for ANS, viscerosomatics, upper and lower extremity OMM with practice quiz.

RTA Assembly Line: 🛠️ The Master...

RTA Assembly Line

RTA Deep Dive

🩸 Vitamin K and the Clotting Cascade: Biochemistry · Vitamin K and Coagulation...

Vitamin K & Coagulation

Thiamine deficiency: dry beriberi strikes peripheral nerves while wet beriberi floods the heart with high-output failure. Causes, signs, and the glucose-before-thiamine trap.

Dry vs Wet Beriberi

Pharmacokinetics & Enzyme Kinetics

Pharmacokinetics & Enzyme Kinetics: Understanding drug movement, metabolism, and enzyme behavior...

CNS Drugs & Hemoglobinopathies

CNS Drugs & Hemoglobinopathies: Pharmacology of chronic pain, opiates, and the sickle cell patient journey...

Collagen Vascular Diseases & Structural Proteins

Collagen Vascular Diseases & Structural Proteins: A Detective Board Approach to Autoimmune Conditions...

Amyloidosis: When your body

Amyloidosis

ATP Famine: Uterus, Vessels & Bladder

The Period That Disappeared: Biochemistry · ATP Famine...

Organ protection hierarchy during energy crisis: brain over heart over kidneys. Why AKI is the accepted price of brain perfusion, plus the Na/K pump as the first sign of cellular injury.

ATP Famine: Triage

ATP Famine: Respiratory & Renal

ATP Famine: Respiratory and Renal: When ATP drops, what happens to your lungs and your kidneys?...

ATP Famine: Repro, Endothelium & Bone Marrow

Repro, Endothelium and Bone Marrow: Five more targets. One root cause. Pick a tab → explore each one....

ATP Famine: Breast, Testicles, Endothelium & Marrow

The Final Wave: Biochemistry · ATP Famine...

Toxicology & Drug Management

☣️ Toxicology and Drug Management: Biochemistry · Toxicology and Drug Management...

Isoelectric Point & Electrophoresis

⚡ Isoelectric Point and Electrophoresis: Biochemistry · Isoelectric Point and Electrophoresis...

NEW

July 31, 2026

July 30, 2026

Crohn Disease vs Ulcerative Colitis

Compare Crohn's disease and ulcerative colitis by distribution, histology, complications, testing, treatment, and surgery.

Diagnose acute appendicitis from pathophysiology, pain migration, examination, imaging, special populations, and complication-directed treatment.

Acute Appendicitis

Cirrhosis and Portal Hypertension

Connect cirrhotic architecture and portal hypertension to decompensation, ascites, varices, encephalopathy, surveillance, and transplant referral.

Diagnose acute pancreatitis, identify its cause and severity, and choose current fluids, feeding, ERCP, antibiotic, and cholecystectomy decisions.

Acute Pancreatitis

Colorectal Cancer: Find It, Stage It, Treat It

Board-focused colorectal cancer epidemiology, presentation, screening, diagnosis, staging, surveillance, and stage-directed treatment.

Jaundice: Build the Differential

A practical prehepatic, hepatocellular, and cholestatic framework using bilirubin fractions, urine clues, injury patterns, and first tests.

Hepatitis serologies: what the result can actually tell you

Deep hepatitis B serology patterns with window period, chronic and resolved infection, vaccination, HBV DNA, pregnancy, reactivation, HAV, HCV, and HDV.

GERD, Erosive Esophagitis, and Peptic Ulcer Disease

A fast clinical sorting hub for GERD, erosive esophagitis, peptic ulcer disease, H pylori, alarm features, testing, and treatment.

Zinc absorption, acquired and inherited deficiency, skin and taste findings, testing limits, replacement, excess-zinc copper deficiency, niacin, and biotin.

Zinc Deficiency

Zenker and Meckel diverticula: follow the wall, pressure, and tissue

Compare Zenker and Meckel diverticula by wall layers, anatomy, embryology, symptoms, complications, and diagnostic testing.

Connect ATP7B failure to hepatic, neurologic, psychiatric, ocular, and hemolytic disease; combine diagnostic tests; and choose chelation, zinc, or transplant.

Wilson Disease

Vitamin and Mineral Absorption

Map iron, folate, calcium, fat-soluble vitamins, bile salts, and vitamin B12 absorption and learn the R-protein-intrinsic-factor pathway and Peyer patches.

Compare gastroschisis, omphalocele, congenital umbilical hernia, and ventral fold closure defects with board-style clues.

Ventral Wall Defects

Tracheoesophageal Anomalies

Learn esophageal atresia, distal tracheoesophageal fistula, H-type fistula, polyhydramnios, tube findings, and gastric gas patterns.

Compare anatomy above and below the pectinate line, including innervation, blood supply, lymphatics, hemorrhoids, fissures, and malignancy.

The Pectinate Line

Inguinal Canal: Routes, Layers and Nerves

Learn inguinal canal walls, deep and superficial rings, Hesselbach triangle, spermatic cord layers, contents, and the myopectineal orifice.

Sulfasalazine and 5-Aminosalicylates

Compare sulfasalazine and mesalamine delivery, ulcerative colitis use, limited Crohn utility, sulfonamide effects, nephrotoxicity, interactions, and monitoring.

Spontaneous bacterial peritonitis: sample, treat and reassess

Diagnose and treat spontaneous bacterial peritonitis with paracentesis, PMN count, cultures, selected albumin use, and prophylaxis.

Identify the cause and transition point of small-bowel obstruction, detect strangulation, distinguish ileus, and choose nonoperative care or surgery.

Small-Bowel Obstruction

Small intestinal bacterial overgrowth: from stasis to a defensible diagnosis

Recognize SIBO risk factors and malabsorption, interpret breath testing limitations, and separate antibiotic induction from recurrence prevention.

Secondary Biliary Obstruction and Cirrhosis

Trace biliary obstruction through cholestatic labs, imaging, infection, decompression, and secondary fibrosis.

Recognize Reye syndrome after viral illness and salicylate exposure, distinguish mimics, and manage its metabolic and neurologic emergencies.

Reye Syndrome

Retroperitoneal structures: follow the lining

Learn primary and secondary retroperitoneal structures, SAD PUCKER exceptions, axial relationships, and clinical spread patterns.

Proton pump inhibitors: target, timing and the reason to continue

Use proton pump inhibitors correctly by mechanism, premeal timing, indication, deprescribing, rebound counseling, adverse-effect evidence, and interaction review.

Differentiate infectious, inflammatory, radiation, and ischemic proctitis using exposure history, examination, targeted testing, and cause-directed treatment.

Proctitis

Primary Sclerosing Cholangitis versus Primary Biliary Cholangitis

Compare PSC and PBC by duct distribution, epidemiology, associations, imaging, histology, treatment, transplant, and cancer surveillance.

PPI-associated hypergastrinemia: read the hormone beside the acid

Replace the legacy PPI hypergastrinemia route with feedback physiology, ECL effects, gastrin interpretation, rebound, differential diagnosis, and safe deprescribing.

Portosystemic Anastomoses

Learn esophageal, paraumbilical, and anorectal portosystemic anastomoses, portal hypertension signs, and TIPS physiology.

Classify porcelain gallbladder calcification, chronic cholecystitis association, imaging mimics, cancer-risk nuance, and individualized management.

Porcelain Gallbladder

Peptic Ulcer Disease and Gastrointestinal Bleeding

Compare gastric and duodenal ulcers, H pylori and NSAID mechanisms, hemorrhage, obstruction, perforation, and upper versus lower GI bleeding.

Pancreatic Secretions and Carbohydrate Absorption

Learn pancreatic enzyme and bicarbonate secretion, trypsin activation, exocrine insufficiency, d-xylose logic, and SGLT1, GLUT5, and GLUT2 transport.

Pancreatic Pseudocyst and Pancreatitis Complications

Distinguish acute pancreatic collections, pseudocyst, and walled-off necrosis, then choose imaging, observation, drainage, and step-up intervention.

Pancreatic Adenocarcinoma

Recognize pancreatic adenocarcinoma, localize disease, interpret imaging and CA 19-9, and frame treatment by resectability.

Pancreas and Spleen Embryology

Learn pancreatic bud derivatives, duct fusion, annular pancreas, pancreas divisum, and mesodermal splenic development.

Use orlistat by its lipase mechanism, meal timing, modest weight effect, gastrointestinal adverse effects, interactions, and patient selection.

Orlistat

Oral and salivary pathologies: location, time and tissue

Compare aphthous ulcers, oral squamous-cell carcinoma, sialolithiasis, sialadenitis, and common benign and malignant salivary tumors.

Octreotide: suppress the output, treat the cause

Use octreotide for variceal hemorrhage, acromegaly, secretory tumors, and selected diarrhea syndromes while monitoring gallbladder, glucose, and cardiac effects.

Normal Gastrointestinal Embryology

Learn foregut, midgut, and hindgut boundaries, stomach rotation, physiologic herniation, and the 270-degree midgut rotation.

Neonatal Hyperbilirubinemia

Distinguish physiologic and feeding-related jaundice from hemolysis, cholestasis, and bilirubin neurotoxicity using AAP 2022 management principles.

Necrotizing enterocolitis

Recognize necrotizing enterocolitis, read pneumatosis and free air, apply Bell-style severity logic, and choose medical versus surgical management.

Recognize collagenous and lymphocytic colitis, biopsy a normal-appearing colon correctly, and treat active or relapsing disease.

Microscopic Colitis

Current MASLD and MASH terminology, fibrosis risk stratification, lifestyle therapy, metabolic treatment, liver-directed therapy, cirrhosis, and HCC risk.

MASLD and MASH

Compare celiac disease, lactose intolerance, exocrine pancreatic insufficiency, tropical sprue, and Whipple disease using tests, histology, and systemic clues.

Malabsorption Syndromes

Lynch syndrome: from tumor testing to family prevention

Understand mismatch-repair genes and MSI, Lynch cancer patterns, universal tumor testing, germline confirmation, surveillance, and prevention.

Locations of Gastrointestinal Secretory Cells

Map parietal, chief, ECL, G, D, I, S, K, and mucous cells through stomach and duodenum and trace vagal acid control.

Liver tissue architecture: follow the path, predict the injury

Learn hepatic lobules, portal triads, sinusoids, canaliculi, Kupffer and stellate cells, dual blood supply, and acinar zones 1 through 3.

Liver Metastases and Secondary Tumors

Recognize liver metastasis sources, spread patterns, imaging clues, biopsy context, and colorectal treatment principles.

Liver Enzymes, AST/ALT Ratio, and Synthetic Function

Interpret hepatocellular, cholestatic, and mixed liver tests using AST and ALT caveats, ALP and GGT, bilirubin, albumin, INR, platelets, and the R factor.

Irritable bowel syndrome: understand the pattern, choose the target

Apply Rome IV criteria, assign IBS subtype, recognize alarm features, limit testing, and choose dietary, behavioral, and subtype-directed therapy.

Diagnose ileocolic telescoping, recognize age-specific lead points, and choose enema reduction or surgery.

Intussusception

Intestinal Malrotation and Midgut Volvulus

Recognize abnormal midgut rotation and fixation, diagnose volvulus quickly, and act before ischemia.

Important Gastrointestinal Ligaments

Learn falciform, hepatogastric, hepatoduodenal, gastrocolic, gastrosplenic, and splenorenal ligaments and their contents.

Ileus and Colonic Pseudo-Obstruction

Recognize ileus, separate it from mechanical obstruction and acute colonic pseudo-obstruction, and treat the cause while supporting the patient.

Hirschsprung Disease: From Distal Aganglionosis to Clinical Decisions

Learn neural crest migration failure, RET associations, distal aganglionosis, neonatal clues, diagnostic tests, enterocolitis, and pull-through surgery.

Hereditary polyposis: from tissue pattern to prevention

Compare APC-associated polyposis, Peutz-Jeghers, juvenile polyposis, and MUTYH polyposis, including cancer risk, surveillance, and prophylactic surgery.

Hepatocellular carcinoma: the tumor and the liver

Apply HCC risk, surveillance, noninvasive imaging diagnosis, AFP limitations, staging, and stage-linked curative, locoregional, and systemic treatment.

2026 ACG-guided hepatic encephalopathy diagnosis, precipitants, ammonia limitations, lactulose, rifaximin, recurrence prevention, and post-TIPS disease.

Hepatic Encephalopathy

Hemochromatosis and Iron Overload

Compare HFE, non-HFE, and secondary iron overload using hepcidin biology, iron studies, MRI, genetics, organ injury, phlebotomy, chelation, and HCC surveillance.

H2 receptor antagonists: target, time and the patient

Compare famotidine, cimetidine, and nizatidine by H2 blockade, indications, tolerance, renal dosing, CNS effects, interactions, and limits versus PPIs.

Gilbert and Crigler-Najjar Syndromes

Compare Gilbert syndrome with Crigler-Najjar types I and II using bilirubin severity, triggers, phenobarbital response, neurotoxicity risk, and treatment.

Gastrointestinal Secretory Products

Learn gastric acid, intrinsic factor, pepsin, mucus, and bicarbonate by source cell, regulation, function, and clinical consequences.

Gastrointestinal Regulatory Substances

Learn gastrin, somatostatin, CCK, secretin, GIP, motilin, VIP, nitric oxide, and ghrelin by source, stimulus, action, and clinical use.

Gastrointestinal Blood Supply and Innervation

Map foregut, midgut, and hindgut structures to celiac, SMA, IMA, vagal, pelvic splanchnic, and sympathetic innervation.

Gastrointestinal angiodysplasia: find the source, explain the recurrence

Recognize gastrointestinal angiodysplasia, its right-colon pattern and systemic associations, and choose endoscopic and recurrence-directed therapy.

Gastritis and Gastric Cancer

Compare acute, H pylori, autoimmune, and hypertrophic gastritis with intestinal and diffuse gastric adenocarcinoma and classic metastatic signs.

Trace cholecystoenteric fistula formation, ectopic stone obstruction, Rigler triad limits, CT diagnosis, surgery, and recurrence.

Gallstone Ileus

Esophagitis and Esophageal Injury

Compare reflux, pill, eosinophilic, infectious, and caustic esophagitis with Mallory-Weiss tears, Boerhaave rupture, and Plummer-Vinson syndrome.

Dubin-Johnson and Rotor Syndromes

Distinguish Dubin-Johnson syndrome from Rotor syndrome using canalicular transport, hepatic reuptake, black liver pigment, and urinary coproporphyrins.

Diverticular disease: anatomy, inflammation and the next decision

Distinguish diverticulosis, diverticular bleeding, and uncomplicated or complicated diverticulitis using CT findings and current management.

Digestive Tract Anatomy and Histology

Learn the MSMS gut-wall layers, enteric plexuses, regional gastrointestinal histology, villi, crypts, Brunner glands, Peyer patches, and slow waves.

Congenital Intestinal Obstruction

Compare duodenal, jejunal, and ileal atresia with hypertrophic pyloric stenosis using timing, emesis, imaging, and mechanism.

Colorectal Cancer Molecular Pathways

A clinically integrated map of CIN, APC, KRAS, TP53, mismatch repair, MSI, BRAF, CIMP, serrated lesions, inherited patterns, testing, and therapy.

Colon polyps: tissue, complete removal and follow-up

Compare hyperplastic polyps, conventional adenomas, and serrated lesions; recognize villous and dysplastic risk; and apply post-polypectomy surveillance concepts.

Chronic Pancreatitis and Exocrine Pancreatic Insufficiency

Connect chronic pancreatic fibrosis and calcification to pain, exocrine insufficiency, diabetes, imaging, fecal elastase, enzyme therapy, and complications.

Chronic mesenteric and colonic ischemia

Distinguish chronic mesenteric ischemia from ischemic colitis by timing, vascular territory, imaging, endoscopy, and severity.

Gallstones and Biliary Colic

Compare cholesterol and pigment stones, biliary colic, ultrasound findings, management, and complications.

Duct Stones and Acute Cholangitis

Recognize bile duct stones and cholangitis using labs, imaging, severity, antibiotics, drainage, and ERCP.

Compare intrahepatic, perihilar, and distal cholangiocarcinoma using risks, cholestasis, imaging, tissue strategy, CA 19-9 limits, and current therapy.

Cholangiocarcinoma

Budd-Chiari Syndrome and Portal Vein Thrombosis

Compare hepatic venous outflow obstruction with portal inflow thrombosis, then connect risk, imaging, and treatment.

Bowel and Gastric Volvulus

Distinguish gastric, midgut, sigmoid, and cecal volvulus by risk group, imaging, ischemia risk, and treatment.

Bismuth, Sucralfate, and Misoprostol

Compare bismuth, sucralfate, and misoprostol mechanisms, clinical uses, interaction spacing, pregnancy implications, and renal and aluminum cautions.

Recognize neonatal cholestasis, understand the limits of ultrasound and HIDA, and move quickly from suspicion to Kasai portoenterostomy or transplant.

Biliary Atresia

Learn bile composition, bile-acid synthesis and enterohepatic circulation, ileal bile-salt loss, oxalate stones, and bilirubin metabolism.

Bile and Bilirubin

Distinguish hemangioma, focal nodular hyperplasia, and hepatic adenoma by demographics, imaging, bleeding risk, molecular subtype, and management.

Benign Liver Tumors

Barrett Esophagus and Esophageal Cancer

Learn Barrett intestinal metaplasia, dysplasia progression, esophageal adenocarcinoma and squamous-cell carcinoma risk factors, locations, and presentation.

Diagnose autoimmune hepatitis using serology, IgG, interface hepatitis, mimic exclusion, immunosuppression, and relapse patterns.

Autoimmune Hepatitis

Compare 5-HT3, dopamine, NK1, antihistamine, antimuscarinic, and cannabinoid antiemetics across chemotherapy, postoperative, motion, and gastroparesis settings.

Antiemetics

Compare loperamide, diphenoxylate, bismuth, bile acid binders, and selected antisecretory therapy with contraindications, interactions, and toxicity risks.

Antidiarrheal Drugs

Compare bulk, osmotic, stimulant, stool-softening, secretagogue, GC-C, 5-HT4, and NHE3 drugs by mechanism, subtype, limitations, and adverse effects.

Anticonstipation Drugs

Compare aluminum, magnesium, and calcium antacids by neutralization, onset, bowel effects, mineral disturbances, renal risk, drug binding, and short-term use.

Antacids

Alpha-1 Antitrypsin Deficiency Liver Disease

Connect SERPINA1 codominant inheritance, hepatocyte polymer retention, pathology, testing, surveillance, and transplantation.

Alcohol-Associated Liver Disease

Clinical reasoning for alcohol-associated steatosis, hepatitis, cirrhosis, severity assessment, treatment, and transplant referral.

Acute Mesenteric Ischemia

Recognize arterial, nonocclusive, and venous acute mesenteric ischemia and act on CTA findings before infarction.

Acute Cholecystitis and Biliary Disease

Distinguish calculous and acalculous cholecystitis using Murphy sign, ultrasound, HIDA, complications, antibiotics, and source control.

Acid suppression physiology

Map acetylcholine, gastrin, histamine, ECL cells, inhibitory feedback, meal timing, and the consequences of sustained gastric acid suppression.

Achalasia and Esophageal Motility Disorders

Compare achalasia, distal esophageal spasm, scleroderma esophagus, and mechanical obstruction using symptoms, barium studies, and manometry.

Abdominal Aorta and Branches

Learn abdominal aortic branches, celiac-SMA-IMA levels, colonic watershed areas, nutcracker syndrome, and superior mesenteric artery syndrome.

Abdominal and Groin Hernias

Compare indirect, direct, femoral, diaphragmatic, hiatal, and Spigelian hernias with vessel relationships and complication risk.

July 29, 2026

July 28, 2026

Stages of Change Communication

Master stages of change, stage-matched counseling, relapse re-entry, and board-style communication choices for smoking cessation.

Healthcare Management and Payment

Compare Medicare, Medicaid, CHIP, COBRA, plan networks, payment incentives, fraud laws, and EMTALA with board-focused decision rules.

Confidentiality, Its Exceptions, and the Duty to Warn

Master confidentiality, HIPAA disclosure pathways, serious-threat exceptions, EPT variability, and patient-centered delivery of difficult news.

Medical Law & Ethics: Consent, Capacity, EMTALA, Malpractice

Learn capacity versus competence, surrogates, advance directives, assent, EMTALA, malpractice, and error disclosure through board-style cases.

Medical Ethics Principles: Autonomy to Justice

Master autonomy, beneficence, nonmaleficence, justice, informed consent, informed refusal, emergency exceptions, and board-style ethics reasoning.

Sexual differentiation: anatomy, hormones, and response

July 16, 2026

July 13, 2026

🤰

Sexual differentiation for clinical practice: AIS vs 5-alpha-reductase deficiency, the hormone levels, external vs internal genitalia, and puberty changes, in an interactive comparison.

Autonomic failure from standing physiology to treatment choices

Autonomic failure for clinical practice: orthostatic hypotension, Shy-Drager and multiple system atrophy, and baroreflex failure, with interactive reflex arcs and board vignettes.

Read any EKG for clinical practice: a stepwise approach to rate, rhythm, axis, intervals, and ischemia, with interactive tracings and pattern recognition built for the exam.

EKG Interpretation

NEW

July 12, 2026

Spinal Cord Tracts and Syndromes

Cord syndromes for clinical practice: Brown-Sequard, anterior cord, central cord, posterior column, and subacute combined degeneration, mapped onto the cord cross-section interactively.

Dermatomes and Root Localization

Dermatome landmarks for clinical practice: the exact nerve root levels for the hand, foot, nipple, umbilicus, and groin, plus how to split a nerve root from a peripheral nerve. Interactive board prep.

Heart failure through pressure, perfusion and treatment

Heart failure for clinical practice: HFrEF vs HFpEF, left vs right failure, the compensatory neurohormonal cascade, and guideline therapy, with interactive pathophysiology.

NEW

June 23, 2026

🛡️

Complement: surfaces, amplification and protection

How the three complement pathways converge on C3b, the amplification loop, MAC formation, and Factor H regulation. Board-style cases on Neisseria, PNH, hereditary angioedema, and aHUS.

Complement Deficiencies: Locate the Break and the Overactive Brake

Complement deficiency syndromes for medical education: C1 inhibitor deficiency and hereditary angioedema, DAF/CD59 loss in PNH, terminal C5 to C9 and properdin and Neisseria, Factor H/I in atypical HUS and dense deposit disease, C3 deficiency, early classical C1/C2/C4 and lupus-like disease.

Immune Cell Lineage: Read the Blood Family Tree

Immune cell lineage and hematopoiesis for Medical Education: the CD34 positive hematopoietic stem cell, common myeloid progenitor, common lymphoid progenitor, surface markers, and board traps.

Electrolyte Emergencies: Crisis Orders

Electrolyte crisis-order drill for hyperkalemia, sodium, calcium, and magnesium: stabilize first, shift or replace when appropriate, correct safely, and avoid the speed traps.

Superior gluteal artery: vessel, nerve, or joint?

The superior gluteal artery for clinical practice: the only structure above piriformis, the abductor supply, and why it is the classic distractor when the femoral head dies in Legg-Calve-Perthes.

The inferior gluteal artery for clinical practice: a terminal branch of the anterior division of the internal iliac that exits below the piriformis with the sciatic nerve. Learn why it is the classic distractor when the femoral-head AVN answer is the medial circumflex femoral.

Inferior gluteal artery

Artery of the Ligamentum Teres and Femoral-Head Perfusion

The artery of the ligament of the head of the femur: origin from the obturator artery, course through the ligamentum teres to the fovea capitis, its minor and regressing role, and why it is the classic distractor in pediatric femoral head avascular necrosis.

Deep Femoral Artery: Trace the Supply, Find the Injury

Why the deep femoral artery is the classic distractor for femoral-head avascular necrosis. Full artery anatomy, the one-step-too-proximal trap, and why the medial circumflex femoral wins.

Medial Circumflex Femoral Artery: Routes to the Femoral Head

The medial circumflex femoral artery is the main blood supply to the femoral head and neck. Why it is the answer in Legg-Calve-Perthes, hip dislocation, SCFE, and femoral neck fracture, with interactive vascular anatomy.

NEW

June 19, 2026

Palliative and Legal Ethics: Hospice, Reporting & Blood Refusal

Board-prep decision lab for palliative care, hospice, mandatory reporting, patient dismissal, abandonment, next-of-kin traps, surrogate decisions, DNR orders, and refusal of blood products.

Abnormal Gait Recognition: Visual Neuro Localizer

Abnormal gait recognition for clinical practice: Parkinsonian, magnetic, ataxic, hemiplegic, scissoring, steppage, Trendelenburg, waddling, antalgic, and choreiform gait patterns with interactive motion drills.

NEW

June 18, 2026

Psoas syndrome: assess the restriction, then the cause

Interactive board-style review for Psoas Syndrome and the Opposite-Motion Rule: high-yield clues, traps, and physician-reviewed board walkthroughs.

Parkinson disease for clinical practice: tremor, rigidity, akinesia, postural instability, substantia nigra loss, Lewy bodies, and alpha-synuclein, with interactive pathology and vignettes.

Parkinson Disease

Alpha blockers: receptor to bedside

Alpha blockers for boards: alpha-1 selective vs non-selective, uses in BPH and pheochromocytoma, and orthostatic hypotension, interactive.

Adrenergic Receptors: Alpha vs Beta Effects

Adrenergic receptors for boards: alpha-1, alpha-2, beta-1, beta-2, and beta-3, where each lives and what it does, with the agonist and antagonist effects, fully interactive.

Diagnose and treat cervical somatic dysfunction for medical board review: OA, AA, and typical C2-C7 coupling, with interactive motion testing and muscle energy walkthroughs.

Cervical OMM

Parkinsonism for boards: the cardinal motor signs, nigrostriatal dopamine loss, and the drug-induced and atypical mimics, with interactive circuits and board vignettes.

Parkinson Disease

Leukemias: ALL vs AML vs CLL vs CML

The four leukemias for boards: ALL, AML, CLL, and CML by age, blast type, and the defining clue, in an interactive comparison.

Galactose and fructose. Follow the sugar, predict the consequence

Sugar metabolism for boards: galactosemia, classic galactosemia vs galactokinase, and fructose intolerance vs essential fructosuria, with the enzyme defects mapped interactively.

Amino Acid Catabolism and Liver Enzymes

Amino acid catabolism for boards: transamination, AST and ALT, glucogenic vs ketogenic amino acids, and ammonia disposal, in one interactive metabolic map for Step 1.

NEW

June 15, 2026

Fascial Subtypes: Why the Joint Capsule Is Deep Fascia

The fascial subtypes for boards: superficial, deep, parietal, visceral, and subserous fascia. Learn why the joint capsule is deep fascia, with an animated layer dissection, a sorting game, and board-style vignettes.

NEW

June 14, 2026

Hemoglobin: binding, release, and oxygen delivery

How hemoglobin's cooperative T to R shift makes the sigmoidal O2 dissociation curve, and what shifts P50 left or right: Bohr effect, 2,3-DPG, CO, and fetal Hb.

NEW

June 13, 2026

Hemoglobin: binding, release, and oxygen delivery

Hemoglobin structure and the oxygen dissociation curve for boards: positive cooperativity and the T to R transition, the Bohr effect, P50, right and left shifts, fetal hemoglobin, sickle cell, CO poisoning, and methemoglobinemia, with an interactive curve and board-style vignettes.

Interactive boards review for Adrenal Insufficiency: high-yield clues, traps, and physician-reviewed board walkthroughs.

Adrenal Insufficiency

Substance Intoxication and Withdrawal

Interactive board-style review of Substance Intoxication and Withdrawal: high-yield clues, traps, and physician-reviewed board walkthroughs.

Anxiety, OCD, and Related Disorders

Interactive board-style review of Anxiety and OCD Disorders: high-yield clues, traps, and physician-reviewed board walkthroughs.

Trauma and PTSD Disorders: Criteria, Context and Care

Interactive board-style review of Trauma and PTSD Disorders: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Eating Disorders: high-yield clues, traps, and physician-reviewed board walkthroughs.

Eating disorders

Somatic Symptoms, Health Anxiety and Functional Neurologic Disorder

Interactive board-style review of Somatic Symptom Disorders: high-yield clues, traps, and physician-reviewed board walkthroughs.

UPDATED 🛡️

Anaphylaxis

Interactive board-style review of Anaphylaxis: high-yield clues, traps, and physician-reviewed board walkthroughs.

UPDATED 👶

Immunization schedules: make every dose count

Interactive board-style review of Immunization Schedules: high-yield clues, traps, and physician-reviewed board walkthroughs.

Acute Intermittent Porphyria

Interactive board-style review of Acute Intermittent Porphyria: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Trace Minerals: high-yield clues, traps, and physician-reviewed board walkthroughs.

Trace Minerals

Interactive board-style review of All Amino Acids: high-yield clues, traps, and physician-reviewed board walkthroughs.

All Amino Acids

Collagen Synthesis and Disorders

Interactive board-style review of Collagen Synthesis and Disorders: high-yield clues, traps, and physician-reviewed board walkthroughs.

Fat-Soluble Vitamins A, D, E, K | clinical reference

Interactive board-style review of Fat-Soluble Vitamins A, D, E, K: high-yield clues, traps, and physician-reviewed board walkthroughs.

B Vitamins: Thiamine, Niacin, and Cofactor Deficiencies

B vitamin deficiency diseases for clinical practice: Wernicke's encephalopathy, pellagra, beriberi, B12 vs folate anemia. Interactive vignettes and mechanism animation.

Interactive board-style review of Animal Farm: high-yield clues, traps, and physician-reviewed board walkthroughs.

Zoonotic Bacteria

Osteoporosis: read the fracture, DXA, risk, and treatment sequence

Interactive board-style review of Osteoporosis: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Which Nerve Feels That Tooth? Maxillary Dental Innervation: high-yield clues, traps, and physician-reviewed board walkthroughs.

Maxillary dental nerves

Smoking Cessation: Treat Dependence and Plan the Next Decision

Interactive board-style review of Smoking Cessation: high-yield clues, traps, and physician-reviewed board walkthroughs.

Tobacco Control: Prevention, Cessation and Clinical Decisions

Interactive board-style review of Tobacco Control: high-yield clues, traps, and physician-reviewed board walkthroughs.

Cystic Fibrosis: From Chloride Transport to Clinical Decisions

Interactive board-style review of Cystic Fibrosis Genetics: high-yield clues, traps, and physician-reviewed board walkthroughs.

Hemophilic arthropathy: from joint bleed to target joint

A board-study deep dive on hemophilic hemarthrosis, chronic hemophilic arthropathy, factor replacement decisions, inhibitors, and common exam traps.

Bleeding and Coagulation Disorder Decoder

Interactive board-style review of Bleeding and Coagulation Disorder Decoder: high-yield clues, traps, and physician-reviewed board walkthroughs.

Hemolytic anemias: locate the destruction

Interactive board-style review of Hemolytic Anemias: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Cellular Injury: high-yield clues, traps, and physician-reviewed board walkthroughs.

Cellular Injury

Breast and axilla masses: trace the tissue and choose the test

Interactive board-style review of Breast and Axilla Masses: high-yield clues, traps, and physician-reviewed board walkthroughs.

Toxidromes and antidotes: recognize the failing physiology

Interactive board-style review of Toxidromes and Antidotes: high-yield clues, traps, and physician-reviewed board walkthroughs.

Foscarnet | Activation, resistance and electrolyte safety

Interactive board-style review of Foscarnet Electrolyte Abnormalities: high-yield clues, traps, and physician-reviewed board walkthroughs.

Glucocorticoids and fragile bone

Interactive board-style review of Glucocorticoid-Induced Osteoporosis: high-yield clues, traps, and physician-reviewed board walkthroughs.

Antiviral Drugs: Mechanisms and Interactions

Interactive board-style review of Antiviral Drugs: high-yield clues, traps, and physician-reviewed board walkthroughs.

Anabolic-androgenic steroids: nuclear receptor mechanism, HPG axis suppression, doping lab fingerprints, and board-style vignettes with interactive matching game.

Anabolic Steroids

Antibiotics: connect the target to the infection

Antibiotics for clinical practice: cell-wall, protein-synthesis, DNA, and folate inhibitors, the coverage and key toxicity of each class, in an interactive mechanism map.

Preeclampsia, Eclampsia and HELLP

Interactive board-style review of Preeclampsia, Eclampsia and HELLP: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Ectopic Pregnancy: high-yield clues, traps, and physician-reviewed board walkthroughs.

Ectopic Pregnancy

Placenta previa and placental abruption

Interactive board-style review of Placenta Previa vs Abruptio Placentae: high-yield clues, traps, and physician-reviewed board walkthroughs.

Cervical Cancer Screening, HPV and Dysplasia

Cervical cancer screening for clinical practice: HPV oncogenes, Pap and HPV co-testing, CIN/LSIL/HSIL management, colposcopy, and board traps, fully interactive.

Polycystic Ovary Syndrome

Interactive board-style review of Polycystic Ovary Syndrome: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Contraception: high-yield clues, traps, and physician-reviewed board walkthroughs.

Contraception

Primary amenorrhea: locate the problem and choose the next step

Interactive board-style review of Primary Amenorrhea: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Aortic Dissection: high-yield clues, traps, and physician-reviewed board walkthroughs.

Aortic Dissection

Abdominal Aortic Aneurysm

Interactive board-style review of Abdominal Aortic Aneurysm: high-yield clues, traps, and physician-reviewed board walkthroughs.

Dyslipidemia and Lipid Management

Interactive board-style review of Dyslipidemia and Lipid Management: high-yield clues, traps, and physician-reviewed board walkthroughs.

Chronic Venous Insufficiency

Interactive board-style review of Chronic Venous Insufficiency: high-yield clues, traps, and physician-reviewed board walkthroughs.

Cardiac Myocyte Action Potential

Interactive board-style review of Cardiac Myocyte Action Potential: high-yield clues, traps, and physician-reviewed board walkthroughs.

Systolic Murmur Localizer

Interactive board-style review of Systolic Murmur Localizer: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Tension Pneumothorax: high-yield clues, traps, and physician-reviewed board walkthroughs.

Tension pneumothorax

Interactive board-style review of Cystic Fibrosis: high-yield clues, traps, and physician-reviewed board walkthroughs.

Cystic Fibrosis

UPDATED 💧

Urinary Tract Infections

Interactive board-style review of Urinary Tract Infections: high-yield clues, traps, and physician-reviewed board walkthroughs.

UPDATED 💧

Sodium and Osmolality: Follow the Water

Interactive board-style review of Sodium and Osmolality Disorders: high-yield clues, traps, and physician-reviewed board walkthroughs.

UPDATED 💧

Nephrolithiasis: protect drainage, explain the chemistry

Interactive board-style review of Nephrolithiasis: high-yield clues, traps, and physician-reviewed board walkthroughs.

Interactive board-style review of Guillain-Barre Syndrome: high-yield clues, traps, and physician-reviewed board walkthroughs.

Guillain-Barre syndrome

Bell Palsy and Facial Localization

Interactive board-style review of Bell Palsy: high-yield clues, traps, and physician-reviewed board walkthroughs.

Acute Ischemic Stroke Management

Interactive board-style review of Acute Ischemic Stroke Management: high-yield clues, traps, and physician-reviewed board walkthroughs.

Peripheral Vertigo and BPPV

Interactive board-style review of Peripheral Vertigo and BPPV: high-yield clues, traps, and physician-reviewed board walkthroughs.

Cervical Radiculopathy: Localize Before You Label

Interactive board-style review of Cervical Roots, Decoded: high-yield clues, traps, and physician-reviewed board walkthroughs.

Sciatica Localizer: Root, Nerve, Plexus, or Canal?

Interactive board-style review of Sciatica, Decoded: high-yield clues, traps, and physician-reviewed board walkthroughs.

Aphasias: Test the Pattern, Localize the Network, Plan the Care

Interactive board-style review of Aphasias: high-yield clues, traps, and physician-reviewed board walkthroughs.

Charcot-Bouchard Aneurysm: From Small-Vessel Injury to Deep Hemorrhage

Interactive board-style review of Charcot-Bouchard Aneurysm: high-yield clues, traps, and physician-reviewed board walkthroughs.

Neurodegeneration Decoder: Anatomy, Circuits and Tempo

Interactive board-style review of Neurodegeneration Decoder: high-yield clues, traps, and physician-reviewed board walkthroughs.

Normal pressure hydrocephalus: from gait to a treatment decision

Normal pressure hydrocephalus for boards: the wet-wacky-wobbly triad, deep hemispheric white matter mechanism, high-volume LP tap test, and VP shunt candidacy.

Cortical Stroke Syndromes: Localize the Dysfunction

Cortical strokes for clinical practice: ACA leg-dominant, MCA face and arm with aphasia, and PCA visual deficits, with the homunculus mapped onto vessels interactively.

Interactive board-style review of Headache Differentials: high-yield clues, traps, and physician-reviewed board walkthroughs.

Headaches

Cranial Dysfunction: Axes, Landmarks, and Clinical Limits

Learn cranial strain patterns for medical board review: torsion, sidebending rotation, vertical and lateral strains at the SBS, with interactive cranial motion diagrams.

Special tests: load the anatomy, then choose the action

The hands-on special tests for medical board review: straight leg raise, Spurling, Trendelenburg, drop arm, and more, with what each maneuver rules in, fully interactive.

Interactive board-style review of Cranial Strain Patterns: high-yield clues, traps, and physician-reviewed board walkthroughs.

Cranial Strain Patterns

Lymphatics: Fluid, Anatomy, and Safe Technique Selection

Interactive board-style review of Lymphatic OMT: high-yield clues, traps, and physician-reviewed board walkthroughs.

Upper and Lower Extremity Findings: Anatomy, Autonomics and Manual Medicine

Extremity OMM for medical board review: shoulder, elbow, wrist, hip, knee, and ankle somatic dysfunction with the autonomic links, in one interactive review.

Interactive board-style review of Zink Common Compensatory Pattern: high-yield clues, traps, and physician-reviewed board walkthroughs.

Zink Patterns

Pituitary tumors and the logic of water balance

June 12, 2026

June 11, 2026

🧬

Posterior pituitary for clinical practice: SIADH vs central and nephrogenic diabetes insipidus, the sodium and osmolality pattern, the water deprivation test, fully interactive.

Adult Prevention & Screening: Who Gets What & When

Adult preventive care that actually shows up: cancer screening ages and intervals, vaccines, and the USPSTF recommendations, in an interactive who-gets-what guide.

NEW

June 8, 2026

🛡️

The Lymphatic System: Organs, Histology and Drainage

Lymphatic system immunology and anatomy for clinical reference: primary organs, secondary organs, histology, thoracic and right lymphatic ducts, node clusters and differentials.

NEW

June 6, 2026

Soft Tissue OMT: Stretch, Traction & Inhibition

Soft tissue technique made test-ready: a group of DIRECT osteopathic techniques that engage the restrictive barrier through parallel traction, perpendicular traction, and direct inhibitory pressure. Learn the board discriminators that separate press from pull, parallel from perpendicular, and direct from indirect, with interactive force-vector games and clinical vignettes.

NEW

June 5, 2026

June 3, 2026

May 31, 2026

May 29, 2026

Anemias: explain cell size and marrow response

Your patient is anemic. That's the easy part. Now figure out why.

May 28, 2026

May 23, 2026

May 22, 2026

May 21, 2026

Stretch more, squeeze harder. Preload curves, the failing heart shift, cardiomyopathy hemodynamics. 25 vignettes with cross-out.

Frank-Starling

Celiac Trunk and Foregut Vascular Anatomy

Left gastric, splenic, common hepatic. Three branches feeding everything above the transverse colon. 25 board vignettes.

Botulism: Recognize the Pattern, Protect Breathing

Descending flaccid paralysis. SNARE cleavage, infant vs foodborne vs wound, BabyBIG, tetanus comparison. 25 board vignettes.

Ureter Blood Supply: Preserve the Connections

Three arteries, three danger zones. Why surgeons ligate the uterine artery and sometimes cut the ureter doing it. 25 vignettes.

Antimetabolites & Drug Interactions

Azathioprine to 6-MP, xanthine oxidase, the allopurinol dose-cut rule. Methotrexate, 5-FU, hydroxyurea. 25 board vignettes.

NEW

May 20, 2026

CO, preload, afterload, Frank-Starling, PV loops, valve lesion parameters, concentric vs eccentric hypertrophy, shock classification, and SVR/PVR. Interactive diagrams and clinical vignettes.

Hemodynamics

NEW

May 18, 2026

Low-Energy State Metabolism

Why low ATP hits fast-dividing tissue first, how reversible injury becomes irreversible, and which organs get protected when energy runs out.

REWORK ⚗️

Glycogen storage diseases

Von Gierke, Pompe, Cori, and McArdle sorted by enzyme, storage site, symptoms, and the board clue that gives each one away.

REWORK 🩸

Clotting cascade: localize the defect, then explain the phenotype

PT, PTT, thrombin, factor X, and the drug families that cut the clotting circuit at each step.

NEW

May 17, 2026

Lead blocks ALA dehydratase and ferrochelatase, so heme synthesis stalls and basophilic stippling explains the paint-chip kid.

Lead Poisoning

Fragile X Syndrome: Repeat Size, Expression and Family Risk

The CGG repeat expansion that silences FMR1, stacks macroorchidism at puberty, and sits behind the #1 cause of inherited intellectual disability.

Abetalipoproteinemia: Build the Particle, Find the Block

MTP mutation traps fat in enterocytes: no chylomicrons form, fat-soluble vitamins A D E K crash, acanthocytes pile up on the smear, and spinocerebellar ataxia closes in.

NEW

May 16, 2026

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Digoxin: stronger contraction, slower conduction, narrow margin

Block the pump. Flood the cell. Save the heart. The drug that poisons the Na/K-ATPase on purpose · and somehow that makes the heart squeeze harder.

NEW 🩺

Prostate Cancer Drugs

Flutamide, leuprolide, degarelix, abiraterone, docetaxel → sort receptor blockade from hormone suppression

ORIGINAL 🧠

Hypothalamic and Pituitary Drugs: Timing, Targets and Water

GnRH, GH, dopamine, ADH, and oxytocin drugs in one board-clean endocrine map

ORIGINAL

May 15, 2026

May 14, 2026

Gut Flora & Drug Metabolism

Bacteria synthesize K, Biotin, Folate. B12 must arrive from diet. Newborn sterile gut has no factory. That is why IM Vitamin K is given at birth.

Ionizing radiation: from energy deposition to cancer

Alpha stops at skin. Beta reaches GI. Gamma hits marrow. Why radiation type determines which cancer comes first.

NEW

May 13, 2026

👶

Newborn Screening: The 48-Hour Heel Stick

The Guthrie card, tandem mass spec, and 35+ conditions caught before symptoms. Why 24 to 48 hours after the first feeding is the only window that matters.

Maple syrup urine disease and the blocked metabolic step

A day-5 newborn with poor feeding, opisthotonos, and a sweet maple smell on the diaper. One broken enzyme complex backs up three amino acids and leucine poisons the brain.

Epidural, subdural, subarachnoid. Same skull, three different layers, three different vessels, three different death notices. By the end you will read the CT before they tell you the trauma.

Intracranial Hemorrhages

Brainstem Stroke Syndromes: Trace the Pathway, Test the Pattern

Four classic patterns. Four tiny arteries. Same trick every time: cranial nerve sign on one side, body sign on the other. That crossed pattern IS the brainstem.

Conus Medullaris + Cauda Equina + LP Landmarks

Where the spinal cord ends and the horse-tail of nerve roots begins. Conus at L1-L2 in adults, L2-L3 in kids. LP at L3-L4 or L4-L5 to stay below. Conus medullaris vs cauda equina syndrome: one is symmetric and early-bladder, the other asymmetric and surgical-emergency.

Spinal Stenosis: When the Canal Squeezes the Cord

The canal narrows. The walking distance shrinks. The shopping cart becomes a walker. Learn the one move that opens the canal back up.

Tyramine Crisis: MAOI Hypertensive Reaction

Hypertensive crisis on MAOIs. Mechanism, forbidden foods, phentolamine first-line, and the serotonin-syndrome trap.

Niemann-Pick disease: sphingomyelinase deficiency, sphingomyelin storage, foam cells, hepatosplenomegaly, cherry-red macula. Types A, B, C side by side with Tay-Sachs.

Niemann-Pick Disease

Wernicke Encephalopathy and Korsakoff Syndrome

Thiamine runs four enzymes the brain cannot live without. Take it away, and the mammillary bodies are the first to fall. Give glucose without thiamine in a chronic drinker, and you just precipitated Wernicke.

Idiopathic Intracranial Hypertension

CSF pressure climbs, the optic discs swell, vision flickers out for seconds at a time. No tumor on imaging. The body is doing it to itself, and the patient is almost always an obese woman of reproductive age.

Tay-Sachs disease: Hex A deficiency, GM2 ganglioside accumulation, cherry-red macula, hyperacusis, no HSM. Ashkenazi infant board pattern, side by side with Niemann-Pick.

Tay-Sachs Disease

PKU: follow the blocked pathway

One missing enzyme. A baby who never makes melanin, dopamine, or serotonin. The musty smell on the diaper that names the disease.

Neural Tube Defects: when the neuropore won't close

Open vs closed NTDs, AFP screening logic, spina bifida spectrum, folate prevention. Built for clinical practice at 2am.

Dandy-Walker Malformation

Missing vermis. Ballooning 4th ventricle. A head that keeps growing because the CSF has nowhere to go. Here is how to spot it on the prenatal scan and never confuse it with Arnold-Chiari again.

Willis-Ekbom. URGE mnemonic. Iron-dopamine pathway. Pramipexole augmentation and the gabapentin save.

Restless Leg Syndrome

A young patient with a copper plumbing problem. The bile drain is broken, the metal piles up, and three organs pay the price: liver, brain, eye.

Wilson Disease

NEW

May 12, 2026

REWORKED Territory Map: inferior Circle-of-Willis view of the brain with six semantic palettes, animated vessel trail on tap, Route / Pattern / Pearl card per artery

Stroke Syndromes

REWORK 🛡️

Free Radicals and the Phagocyte Respiratory Burst

FIXED cramped bleach-circuit diagram: viewBox widened, nodes spaced apart, enzyme labels no longer overlap. BUFFED active nodes with a breathing glow pulse so the active step feels alive.

FIX 🔬

Cancer Metastasis Patterns

REWORKED Where Cancer Lands: animated grey-white junction diagram, body map redesign, most common liver cancer reveal

NEW 💀

Prescryption v3

v3 schema is live across 60 cards. Map gen is procedural now: three distinct events from a pool of five, no template repeats. Elite mini-boss nodes show up 50% of the time pre-boss, branching forks 55% of the time per slot. Attending's Office and Consult are wired. A 10-relic system picks 3 at run start and again after every elite win. Map got redesigned as a mahogany tabletop with stamped wax seals per node. Death-screen restart is fixed, tooltips auto-hide at 15s with an opacity fade. Landing now shows the real deck size: 7 rotations, 1,965 drugs, 686 diseases.

PATCH 🧘

OMM Fundamentals: From Examination to Treatment Choice

TART criteria, barrier concepts, direct vs indirect technique, and the osteopathic models - the OMM foundation every DO student needs.

NEW

May 11, 2026

⚛

Cholesterol Synthesis & Regulation

Added tap-to-unblur memory hook cards to the Hook section. Night Shift Factory, Statin Side Effect logic, PCSK9 bouncer.

BUFF ⚛

β-Oxidation: From Fasting Signal to Clinical Pattern

Bugfix: duplicate h1/hero block removed. Page now has one clean hero with related-page links inline.

BUGFIX

May 6, 2026

🦴

Radial Head: Rotation, Examination, and Safe Decisions

Supination tests, Spencer protocol, HVLA/MET/BLT for a radial head stuck in the past. Segmental diagnosis chain with clinical vignettes.

NEW

May 5, 2026

🦴

Autonomic Spinal Levels: Trace the Pathway Before the Pattern

T1-L2 SNS vs S2-4 PSNS spinal level rules, Chapman reflex points, facilitated segment logic for board stems.

NEW 🦴

Cranial Parasympathetic Techniques: Anatomy, Contact and Clinical Judgment

CV4, EV4, fluid drive mechanics, four vagus-governed cranial nerves with tap-to-reveal lesion patterns.

NEW

May 1, 2026

New interactive page. 55 high-yield memory hooks and acronyms for psychiatry, GI, renal, endocrine, and more. Rapid-fire cards for final review.

Mnemonics Hub

April 29, 2026

New page. Rate-limiting enzyme, bypass reactions, glucagon vs insulin regulation. Board quiz: metformin mechanism + F2,6BP inhibition.

Gluconeogenesis

April 28, 2026

Viscerosomatic reflexes: pathways, patterns and limits

New page. Spinal segment-to-organ map: T1-T5 cardiac, T6-T9 GI, L1-L2 pelvic. Diagnostic and treatment implications.

Gram Stain Chart: From Appearance to Clinical Decisions

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New page. 37 organisms with stain, morphology, virulence, and first-line treatment. Interactive filter by category + pattern quiz.

Schizophrenia and mood disorders

New page. Positive/negative symptoms, DSM criteria, mood episode types, bipolar I vs II, cyclothymia.

New page. CRAB criteria, SPEP M-spike, Bence Jones proteins, smoldering vs active disease, MGUS progression risk.

Multiple Myeloma & MGUS

TORCH and other perinatal infections: anatomy, timing and action

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New page. Toxo, Other, Rubella, CMV, HSV. Timing of transmission, fetal findings, maternal treatment.

Dementias: Timing, Networks, and Treatable Contributors

New page. Alzheimer's, Lewy body, FTD, vascular, CJD. Tau vs TDP-43, cortical vs subcortical pattern, reversible mimics.

Antipsychotics, Mood Stabilizers, and Anxiolytics

New page. Typical vs atypical, EPS ladder, lithium toxicity, benzo mechanism and reversal.

Lung cancers: tissue, physiology, and treatment decisions

New page. SCC/ADC/SCLC/large cell locations and staining. Paraneoplastic syndromes, Pancoast, Lambert-Eaton, SVC syndrome.

ARDS and the lung that needs protection

New page. Berlin criteria, lung-protective ventilation, plateau pressure, driving pressure, prone positioning.

PE and DVT from probability to treatment

New page. Wells score, V/Q vs CTA-PE, submassive vs massive, tPA criteria, PERC rule, Virchow's triad.

New page. Vaughan Williams I-IV, Na/K/Ca/beta targets, pro-arrhythmia risks, Torsades triggers.

Antiarrhythmics

Cardiomyopathies. Shape, tissue and clinical decisions

New page. Dilated/hypertrophic/restrictive patterns, LVEF, HOCM dynamic outflow obstruction, maneuvers that worsen/improve murmur.

New page. G1/S/G2/M checkpoints, p53 guardian role, Rb tumor suppressor, cyclins/CDKs, intrinsic vs extrinsic apoptosis.

Cell Cycle & Apoptosis

New page. MMR/NER/BER/NHEJ mechanisms, microsatellite instability, Lynch syndrome, xeroderma pigmentosum, BRCA.

DNA Replication & Repair

Purine & Pyrimidine Synthesis

New page. De novo vs salvage, gout pathway, adenosine deaminase deficiency = SCID.

April 27, 2026

New page. Glycogenesis vs glycogenolysis, G6P branch point, liver vs muscle glycogen function, hormonal regulation.

Glycogen metabolism

clinical medicine Study Path

New page. clinical practice timeline, resource stack, spaced repetition schedule, high-yield topic priority list.

Insulinoma and the hypoglycemia critical sample

🧬

New page. Whipple's triad, fasting hypoglycemia, C-peptide elevated, 72-hour fast, surgical resection.

Sarcoidosis: diagnosis, organ risk, and treatment

Bilateral hilar LAD, high calcium, non-caseating granulomas · detective game

Lung abscess: follow the route, locate the collection

Aspiration route, foul sputum, air-fluid level, anaerobes · RLL focus

Antidiabetic drugs. Match the mechanism to the person

GLP-1 vs SGLT2 mortality wins, HF traps, 6-class duel · decision tree

Piriformis and Deep Gluteal Pain

Deep buttock pain, sciatic trap, figure-4 stretch, externally rotated hip

Lacunar syndromes, no cortical signs, PLIC vs thalamus · brain map

Lenticulostriate Strokes

Vasculitis: read the vessel before naming the disease

Vessel size triage, ANCA map, GCA to HSP, 12 vessels · sorting game

Adhesion vs aggregation, BS vs Glanzmann vs vWD triage · animated plug builder

Platelets & Hemostasis

Drugs of the Clotting Cascade

Cascade map, PTT vs PT monitoring, reversal agents · drug target overlays

Congenital adrenal hyperplasia: read the blocked steroid pathway

21-OH vs 11-OH vs 17-OH, salt-wasting, virilization, HTN · mnemonic grid

Lumbar Dysfunctions: From Palpatory Findings to a Coherent Diagnosis

Lumbar TART, type I/II mechanics

Innominate Shears, Flares, and Pubic Shears

Superior/inferior shear, innominate flares

Innominate Rotations: Position, Direction, and Clinical Judgment

Anterior/posterior innominate rotation diagnosis and treatment

Lumbar and Pelvic Counterstrain: Landmarks Before Positions

Tender point locations, strain-counterstrain technique

Insulinoma and the hypoglycemia critical sample

Insulinoma workup, Whipple triad, hypoglycemia causes

Pulmonary Physiology: Air, Blood and Pressure

V/Q gradient, alveolar cells, airway obstruction physics, pneumoconioses · all four under one roof.

NEW

April 25, 2026

Delayed P2, RBBB, pulmonic stenosis · animated phonocardiogram

Wide S2 Split

Delayed A2, LBBB, severe AS · animated split timing diagram

Paradoxical S2 Split

Mortality drugs vs symptom drugs, aspirin dosing, drug sorting game

MI ED Meds: MONA-BAH

EKG Lead I: Vector from RA to LA

Lead I EKG anatomy, axis determination, lateral MI · animated axis compass

MS, TS, Austin Flint, Graham Steell · split-screen comparison

Diastolic Rumble

Urea cycle: localize the block and protect the brain

OTC, CPS I defects, ammonia routing · 5-step relay race pathway builder

Pentose phosphate pathway

G6PD deficiency, NADPH, oxidative vs non-oxidative · trigger game

Fatty Acid Synthesis vs Beta-Oxidation

Malonyl-CoA switch, fed vs fasted toggle, cytosol vs mito compartments

Enzymes, inhibition and energy metabolism

Km/Vmax, competitive vs non-competitive, ETC poisons · interactive chain

Cancer Pathology: Lineage, Spread, and Driver Logic

Tumor markers, oncogenes, IHC stains, MEN syndromes, paraneoplastic, psammoma 4 mnemonic.

NEW

April 24, 2026

MG, Parkinson's, MS drug cards · neuro pharmacology roguelite deck

Prescryption · Neuro

Drug and neuro deck selectors · medical roguelite hub

Prescryption

Glucagonoma Syndrome: NME, Catabolism, and Pancreatic NET Reasoning

Necrolytic migratory erythema, the 4 D's, alpha-cell tumor · clinical medicine trap on glucagon excess.

De-escalation ladder, B52 cocktail breakdown, capacity criteria, admit/discharge tree

The Agitated Patient

Beta blockers: predict the tissue response

Selective vs non-selective classifier, B1 selectivity breakdown

NEW

April 23, 2026

💎

Actinic keratosis and the epidermal boundary

Lesion ID game, UV timeline, field cancerization

GH-IGF1 axis, comparison tabs, treatment stepper

Gigantism (GH Excess)

Phonocardiogram, hemodynamic maneuver tabs, remodeling diagram

Mitral Regurgitation

Metabolic chain builder, elimination game

Pyloric Stenosis

Inferior MI, right ventricular failure, and AV block

Coronary diagram, EKG pattern game, treatment stepper

Bartholin Cysts and Abscesses

Gland location game, treatment ladder

NEW

April 19, 2026

🔍

Spotlight Search

Cmd+K to search all 80+ topics. Subject icons, fuzzy scoring, keyboard nav.

NEW

April 12, 2026

💧

Diuretics and the nephron

Interactive nephron map, ototoxicity, calcium trap

Histology battle cards, adult vs pediatric, pseudopalisades

Brain Tumors

Cluster sorting game, defense mechanisms, diagnostic criteria

Personality disorders

Hemophilia & the Coag Cascade

Cascade diagram, factor X step, mixing studies

Basal ganglia anatomy, circuits, and clinical localization

Interactive cross-section, putamen vs GP, Charcot-Bouchard

Iron Deficiency Anemia Workup

Demographic decision tree, stool guaiac, haptoglobin trap

Renal artery stenosis and RAAS

Animated cascade, JGA hyperplasia, resistant HTN

NEW 🫀

Abdominal Aortic Branches in Anatomy and Clinical Decisions

Interactive vertebral levels, ovarian artery at L2

Medication Adherence: Exposure, Barriers and Safe Treatment

Elimination game, therapeutic alliance, adherence strategies

NEW 🗣

Medical Interpreter Rules and Meaningful Communication

Decision tree, 2 exceptions, emergency exception for minors

NEW

April 8, 2026

Iron lab interpreter, thalassemia gene deletion counter

Microcytic Anemias

Macrocytic, Normocytic Anemias & PNH

MCV triage station, complement attack simulator

Post-MI complications through rhythm, flow, and tissue failure

Timeline of complications, Dressler's, papillary muscle rupture

NEW

April 7, 2026

🃏

Prescryption Card Game

New medical card game → diagnose patients, outsmart The Attending

Cranial nerves and clinical localization

Full redesign → battle cards, spacious board traps, new theme

Battle cards, SS vs NMS comparison, emergency cards

Antidepressants

Skin cancers through tissue, invasion and risk

BCC vs SCC vs Melanoma → new theme, elimination game

Adrenal masses: hormones, feedback, and the incidentaloma fork

Conn vs Cushing vs Pheo → full redesign

REBUILT ⚡

Seizures and epilepsy

EEG viewer, AED tables, status epilepticus protocol

Demyelinating diseases: localization, timing and treatment

MS vs GBS vs CIDP → decision tree, elimination game

Neuromuscular Junction Disorders: MG, LEMS and Botulism

Myasthenia vs Lambert-Eaton → new theme

REBUILT 🤲

Movement Disorders: Parkinson, Huntington, Tremors

Tremor demos, drug tables, Parkinson's vs essential tremor

REBUILT 🩹

Coagulation: connect assays to bleeding and thrombosis

Cascade diagram, mixing studies, disease cards

Heart murmurs. Timing, pressure and bedside decisions

Battle cards, maneuver tables, new theme

20 pathognomonic findings, matching game, decision tree

Classic Derm Findings

REBUILT 💥

Hypersensitivity Reactions (Types I-IV)

16-disease drag-drop sorting, Type II vs III deep-dive

REBUILT 🦴

Fibular Head Somatic Dysfunction

Interactive seesaw diagram, muscle energy positioning